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Steroid 11 Beta Hydroxylase

A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).

108+ PubMed studies analyzed · 1 RCTs · Evidence Score: 46.3

Research Domains

Steroid 11 Beta Hydroxylase has been studied across 13 research domains including 🫘 Kidney, ❤️ Cardiovascular, ⚡ Energy & Fatigue, 🧬 Hormones, 🔬 Oncology. The primary research focus is 🫘 Kidney with 75% of studies addressing this area.

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This evidence profile for Steroid 11 Beta Hydroxylase is generated deterministically from 108 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.