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Steroid 17 Alpha Hydroxylase

A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.

105+ PubMed studies analyzed · 1 RCTs · Evidence Score: 45.1

Research Domains

Steroid 17 Alpha Hydroxylase has been studied across 20 research domains including 🫘 Kidney, 🧬 Hormones, 💪 Strength & Power, 🫁 Liver & Detox, ♀♂ Sexual Health. The primary research focus is 🫘 Kidney with 45% of studies addressing this area.

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This evidence profile for Steroid 17 Alpha Hydroxylase is generated deterministically from 105 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.