An NADPH-dependent P450 enzyme that plays an essential role in the sterol biosynthetic pathway by catalyzing the demethylation of 14-methyl sterols such as lanosterol. The enzyme acts via the repeated hydroxylation of the 14-methyl group, resulting in its stepwise conversion into an alcohol, an aldehyde and then a carboxylate, which is removed as formic acid. Sterol 14-demethylase is an unusual cytochrome P450 enzyme in that it is found in a broad variety of organisms including ANIMALS; PLANTS; FUNGI; and protozoa.
Sterol 14 Demethylase has been studied across 6 research domains including 🫁 Liver & Detox, 🧠 Focus & Attention, ❤️ Cardiovascular, 🏋️ Muscle & Hypertrophy, 🔬 Oncology. The primary research focus is 🫁 Liver & Detox with 17% of studies addressing this area.
This evidence profile for Sterol 14 Demethylase is generated deterministically from 47 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.