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Theophylline

A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.

296+ PubMed studies analyzed · 10 RCTs · Evidence Score: 41.8

Research Domains

Theophylline has been studied across 9 research domains including 🫁 Respiratory, 😴 Sleep, 🫘 Kidney, ❤️ Cardiovascular, 🔬 Inflammation. The primary research focus is 🫁 Respiratory with 34% of studies addressing this area.

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This evidence profile for Theophylline is generated deterministically from 296 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.