An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
Triggering Receptor Expressed On Myeloid Cells 1 has been studied across 19 research domains including 😴 Sleep, 🔬 Inflammation, 🔬 Oncology, 🛡️ Immunity, 🫁 Respiratory. The primary research focus is 😴 Sleep with 37% of studies addressing this area.
This evidence profile for Triggering Receptor Expressed On Myeloid Cells 1 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.