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Tumor Necrosis Factor Alpha

Tumor Necrosis Factor-alpha Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

300+ PubMed studies analyzed · 1 RCTs · Evidence Score: 46.1

Research Domains

Tumor Necrosis Factor Alpha has been studied across 21 research domains including 🔬 Oncology, 🔬 Inflammation, 🛡️ Immunity, 🦴 Bone & Joint, 🫁 Liver & Detox. The primary research focus is 🔬 Oncology with 99% of studies addressing this area.

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This evidence profile for Tumor Necrosis Factor Alpha is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.