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Type Vii Secretion Systems

a MYCOLIC ACID-containing outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These are also known as ESX secretion systems because the first to be discovered is involved in secreting major virulence factors EsxA and EsxB. There are several subtypes of T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes share some core components including an inner membrane channel-forming ATPase complex, a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing membrane.

103+ PubMed studies analyzed · Evidence Score: 43.2

Research Domains

Type Vii Secretion Systems has been studied across 10 research domains including 🔬 Inflammation, 🔬 Oncology, 🫁 Respiratory, 🔥 Metabolic, 🛡️ Immunity. The primary research focus is 🔬 Inflammation with 5% of studies addressing this area.

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This evidence profile for Type Vii Secretion Systems is generated deterministically from 103 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.