BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/CASP8
MOLECULAR TARGET

CASP8

Caspase-8

123 compounds · BiohacksAI corpus v20260307-01

123
compounds
Compounds
123
Gene Symbol
CASP8
NCBI Gene
—

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About CASP8

CASP8 (Caspase-8) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 123 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting CASP8 (50)
1
Pralnacasan
2.08
confidence
2
Prunella Vulgaris
1.00
confidence
3
Platycodon Grandiflorus
1.00
confidence
4
Polygonum Cuspidatum
1.00
confidence
5
Portulaca Oleracea
500
studies
1.00
confidence
6
Achyranthes Bidentata
1.00
confidence
7
Agastache Rugosa
1.00
confidence
8
Allium Sativum
500
studies
1.00
confidence
9
Aloe Vera
1.00
confidence
10
Arctium Lappa
1.00
confidence
11
Areca Catechu
199
studies
1.00
confidence
12
Artemisia Capillaris
1.00
confidence
13
Aster Tataricus
1.00
confidence
14
Atractylodes Macrocephala
1.00
confidence
15
Bletilla Striata
1.00
confidence
16
Bupleurum Chinense
1.00
confidence
17
Carthamus Tinctorius
1.00
confidence
18
Centella Asiatica
499
studies
1.00
confidence
19
Chaenomeles Speciosa
1.00
confidence
20
Citrus Reticulata
1.00
confidence
21
Crataegus Pinnatifida
1.00
confidence
22
Curculigo Orchioides
116
studies
1.00
confidence
23
Curcuma Longa
500
studies
1.00
confidence
24
Cuscuta Chinensis
1.00
confidence
25
Cynomorium Songaricum
1.00
confidence
26
Dimocarpus Longan
1.00
confidence
27
Ephedra Sinica
1.00
confidence
28
Eriobotrya Japonica
1.00
confidence
29
Eucommia Ulmoides
1.00
confidence
30
Foeniculum Vulgare
499
studies
1.00
confidence
31
Forsythia Suspensa
1.00
confidence
32
Fritillaria Cirrhosa
1.00
confidence
33
Gentiana Macrophylla
1.00
confidence
34
Ginkgo Biloba
299
studies
1.00
confidence
35
Glycine Max
1.00
confidence
36
Glycyrrhiza Uralensis
1.00
confidence
37
Ligusticum Chuanxiong
1.00
confidence
38
Lilium Lancifolium
1.00
confidence
39
Litchi Chinensis
1.00
confidence
40
Lithospermum Erythrorhizon
1.00
confidence
41
Lobelia Chinensis
1.00
confidence
42
Lonicera Japonica
1.00
confidence
43
Magnolia Biondii
1.00
confidence
44
Morus Alba
1.00
confidence
45
Nelumbo Nucifera
0
studies
1.00
confidence
46
Paeonia Lactiflora
1.00
confidence
47
Panax Ginseng
300
studies
1.00
confidence
48
Panax Notoginseng
1.00
confidence
49
Perilla Frutescens
1.00
confidence
50
Pinellia Ternata
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.