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BiohacksAI/Targets/DHI1
MOLECULAR TARGET

DHI1

11-beta-hydroxysteroid dehydrogenase 1

69 compounds · BiohacksAI corpus v20260307-01

69
compounds
Compounds
69
Gene Symbol
DHI1
NCBI Gene
—

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About DHI1

DHI1 (11-beta-hydroxysteroid dehydrogenase 1) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 69 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting DHI1 (50)
1
Bdb Merck 544 3 Adamantan 1 Yl 6 7 8 9 Tetrahydro 5h 1 2 4 Triazolo 4 3 A Azepine Ch
3
studies
1.10
confidence
2
Bdb Chembl4748750
2
studies
0.69
confidence
3
Bdb Chembl4746745
2
studies
0.69
confidence
4
Bdb Chembl4747534
2
studies
0.69
confidence
5
Bdb Chembl4779054
2
studies
0.69
confidence
6
Bdb Chembl4788862
2
studies
0.69
confidence
7
Bdb R 3 3 Cyano Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoyl Adamanta
2
studies
0.69
confidence
8
Bdb R 3 5 Cyano Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoyl Adamanta
2
studies
0.69
confidence
9
Bdb R 3 6 Trifluoromethyl Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoy
2
studies
0.69
confidence
10
Bdb R 3 3 Trifluoromethyl Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoy
2
studies
0.69
confidence
11
Bdb R 3 5 Trifluoromethyl Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoy
2
studies
0.69
confidence
12
Bdb S 3 3 Trifluoromethyl Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoy
2
studies
0.69
confidence
13
Bdb 1 2 Adamantyl 3 Benzylpyrrolidin 2 One Chembl218286
2
studies
0.69
confidence
14
Bdb 1 Piperidin 1 Yl Cyclopropanecarboxylic Acid 5 Hydroxy Adamantan 2 Yl Amide Chem
2
studies
0.69
confidence
15
Bdb 1r 3r 4s 7s 4 2 2 Chlorophenoxy 2 Methylpropanamido Adamantane 1 Carboxylic Acid
2
studies
0.69
confidence
16
Bdb 1r 3r 4s 7s 4 2 2 Chlorophenoxy 2 Methylpropanamido N Methanesulfonyladamantane
2
studies
0.69
confidence
17
Bdb 1r 3r 4s 7s 4 2 3 Chlorophenoxy 2 Methylpropanamido Adamantane 1 Carboxylic Acid
2
studies
0.69
confidence
18
Bdb 1r 3r 4s 7s 4 2 4 Chlorophenoxy 2 Methylpropanamido N Pyridin 4 Ylmethyl Adamant
2
studies
0.69
confidence
19
Bdb 2 1 Adamantan 2 Yl Carbamoyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Yl Acetic
2
studies
0.69
confidence
20
Bdb 2 1 Adamantan 2 Yl Carbamoyl 4 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y
2
studies
0.69
confidence
21
Bdb 2 1 Adamantan 2 Yl Carbamoyl 5 Chloro 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y
2
studies
0.69
confidence
22
Bdb 2 1 Adamantan 2 Yl Carbamoyl 5 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y
2
studies
0.69
confidence
23
Bdb 2 1 Adamantan 2 Yl Carbamoyl 6 Chloro 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y
2
studies
0.69
confidence
24
Bdb 2 1 Adamantan 2 Yl Carbamoyl 6 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y
2
studies
0.69
confidence
25
Bdb 2 1 Adamantan 2 Yl Carbamoyl 7 Bromo 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Yl
2
studies
0.69
confidence
26
Bdb 2 1 Adamantan 2 Yl Carbamoyl 7 Chloro 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y
2
studies
0.69
confidence
27
Bdb 2 1 Adamantan 2 Yl Carbamoyl 7 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y
2
studies
0.69
confidence
28
Bdb 2 2 6 Dichloro 4 Fluoro Phenoxy 2 Methyl N 5 Sulfamoyl Adamantan 2 Yl Propionami
2
studies
0.69
confidence
29
Bdb 2 2 Chloro 4 Fluorophenoxy 2 Methyl N 1r 2s 5r 7s 5 1h 1 2 3 4 Tetrazol 5 Yl Ada
2
studies
0.69
confidence
30
Bdb 2 2 Chloro Phenoxy 2 Methyl N 5 Sulfamoyl Adamantan 2 Yl Propionamide Chembl2393
2
studies
0.69
confidence
31
Bdb 2 2 Chloro Phenoxy N 5 Methanesulfonyl Adamantan 2 Yl 2 Methyl Propionamide Chem
2
studies
0.69
confidence
32
Bdb 2 3 Chloro Phenoxy 2 Methyl N 5 Sulfamoyl Adamantan 2 Yl Propionamide Chembl3991
2
studies
0.69
confidence
33
Bdb 2 3r 1 Adamantan 2 Yl Carbamoyl 7 Bromo 2 3 Dihydrospiro Indene 1 4 Piperidine 3
2
studies
0.69
confidence
34
Bdb 2 3s 1 Adamantan 2 Yl Carbamoyl 7 Bromo 2 3 Dihydrospiro Indene 1 4 Piperidine 3
2
studies
0.69
confidence
35
Bdb 2 Hexahydro 2 5 Methanopentalen 3a 1h Ylamino 1 Thia 3 Azaspiro 4 4 Non 2 En 4 O
2
studies
0.69
confidence
36
Bdb 3 3 Dimethyl 1 5 1h Tetrazol 5 Yl Adamantan 2 Yl 4 5 Trifluoromethyl Pyridin 2 Y
2
studies
0.69
confidence
37
Bdb 3 3 Dimethyl Pentanedioic Acid 5 Carbamoyl Adamantan 2 Yl Amide Cyclopropylamide
2
studies
0.69
confidence
38
Bdb 3 3 Dimethyl Pentanedioic Acid Cyclopropylamide 5 Hydroxy Adamantan 2 Yl Amide C
2
studies
0.69
confidence
39
Bdb 3 Adamantan 1 Yl 5 6 7 8 9 10 Hexahydro 1 2 4 Triazolo 4 3 A Azocine Chembl25677
2
studies
0.69
confidence
40
Bdb 3 Benzyl 1 5 Hydroxy Adamantan 2 Yl Pyrrolidin 2 One Chembl376306
2
studies
0.69
confidence
41
Bdb 3 Phenyl Adamantan 1 Yl Piperidin 1 Yl Methanone Chembl1088379
2
studies
0.69
confidence
42
Bdb 4 1 4 5 Trifluoromethyl Pyridin 2 Yl Piperazin 1 Yl Cyclopropanecarbonyl Amino A
2
studies
0.69
confidence
43
Bdb 4 2 3 3 Difluoro Piperidin 1 Yl Butyrylamino Adamantane 1 Carboxylic Acid Amide
2
studies
0.69
confidence
44
Bdb 4 2 Methyl 2 4 5 Trifluoromethyl Pyridin 2 Yl Piperazin 1 Yl Propionylamino Adam
2
studies
0.69
confidence
45
Bdb 4 3 3 Dimethyl 2 Oxo 4 4 1 2 4 Triazol 1 Yl Phenoxymethyl Pyrrolidin 1 Yl Adaman
2
studies
0.69
confidence
46
Bdb 4 4 4 Imidazol 1 Yl Phenoxymethyl 3 3 Dimethyl 2 Oxo Pyrrolidin 1 Yl Adamantane
2
studies
0.69
confidence
47
Bdb 4 Amino 3 5 Dichloro Phenyl 2 Aza Tricyclo 3 3 1 1 3 7 Dec 2 Yl Methanone Chembl
2
studies
0.69
confidence
48
Bdb 5 5 Diethyl 2 Tricyclo 3 3 1 0 3 7 Nonan 3 Ylamino 4 5 Dihydro 1 3 Thiazol 4 One
2
studies
0.69
confidence
49
Bdb 5 Ethyl 5 Methyl 2 Tricyclo 3 3 1 0 3 7 Nonan 3 Ylamino 4 5 Dihydro 1 3 Thiazol
2
studies
0.69
confidence
50
Bdb Chembl2152223
2
studies
0.69
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.