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Evidence-Based Biohacking

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BiohacksAI/Targets/DHI2

MOLECULAR TARGET

DHI2

11-beta-hydroxysteroid dehydrogenase type 2

58 compounds · BiohacksAI corpus v20260307-01

58

compounds

Compounds

58

Gene Symbol

DHI2

NCBI Gene

—

Looking for compounds that interact with DHI2?

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About DHI2

DHI2 (11-beta-hydroxysteroid dehydrogenase type 2) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 58 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting DHI2 (50)

1

Bdb Merck 544 3 Adamantan 1 Yl 6 7 8 9 Tetrahydro 5h 1 2 4 Triazolo 4 3 A Azepine Ch

3

studies

1.10

confidence

2

Bdb Chembl4748750

2

studies

0.69

confidence

3

Bdb R 3 3 Cyano Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoyl Adamanta

2

studies

0.69

confidence

4

Bdb R 3 5 Cyano Pyridin 2 Ylamino Pyrrolidine 1 Carboxylic Acid 5 Carbamoyl Adamanta

2

studies

0.69

confidence

5

Bdb 1 2 Adamantyl 3 Benzylpyrrolidin 2 One Chembl218286

2

studies

0.69

confidence

6

Bdb 1 Piperidin 1 Yl Cyclopropanecarboxylic Acid 5 Hydroxy Adamantan 2 Yl Amide Chem

2

studies

0.69

confidence

7

Bdb 1r 3r 4s 7s 4 2 2 Chlorophenoxy 2 Methylpropanamido Adamantane 1 Carboxylic Acid

2

studies

0.69

confidence

8

Bdb 1r 3r 4s 7s 4 2 2 Chlorophenoxy 2 Methylpropanamido N Methanesulfonyladamantane

2

studies

0.69

confidence

9

Bdb 1r 3r 4s 7s 4 2 3 Chlorophenoxy 2 Methylpropanamido Adamantane 1 Carboxylic Acid

2

studies

0.69

confidence

10

Bdb 1r 3r 4s 7s 4 2 4 Chlorophenoxy 2 Methylpropanamido N Pyridin 4 Ylmethyl Adamant

2

studies

0.69

confidence

11

Bdb 2 1 Adamantan 2 Yl Carbamoyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Yl Acetic

2

studies

0.69

confidence

12

Bdb 2 1 Adamantan 2 Yl Carbamoyl 4 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y

2

studies

0.69

confidence

13

Bdb 2 1 Adamantan 2 Yl Carbamoyl 5 Chloro 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y

2

studies

0.69

confidence

14

Bdb 2 1 Adamantan 2 Yl Carbamoyl 5 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y

2

studies

0.69

confidence

15

Bdb 2 1 Adamantan 2 Yl Carbamoyl 6 Chloro 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y

2

studies

0.69

confidence

16

Bdb 2 1 Adamantan 2 Yl Carbamoyl 6 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y

2

studies

0.69

confidence

17

Bdb 2 1 Adamantan 2 Yl Carbamoyl 7 Bromo 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Yl

2

studies

0.69

confidence

18

Bdb 2 1 Adamantan 2 Yl Carbamoyl 7 Chloro 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y

2

studies

0.69

confidence

19

Bdb 2 1 Adamantan 2 Yl Carbamoyl 7 Methyl 2 3 Dihydrospiro Indene 1 4 Piperidine 3 Y

2

studies

0.69

confidence

20

Bdb 2 2 6 Dichloro 4 Fluoro Phenoxy 2 Methyl N 5 Sulfamoyl Adamantan 2 Yl Propionami

2

studies

0.69

confidence

21

Bdb 2 2 Chloro 4 Fluorophenoxy 2 Methyl N 1r 2s 5r 7s 5 1h 1 2 3 4 Tetrazol 5 Yl Ada

2

studies

0.69

confidence

22

Bdb 2 2 Chloro Phenoxy 2 Methyl N 5 Sulfamoyl Adamantan 2 Yl Propionamide Chembl2393

2

studies

0.69

confidence

23

Bdb 2 2 Chloro Phenoxy N 5 Methanesulfonyl Adamantan 2 Yl 2 Methyl Propionamide Chem

2

studies

0.69

confidence

24

Bdb 2 3 Chloro Phenoxy 2 Methyl N 5 Sulfamoyl Adamantan 2 Yl Propionamide Chembl3991

2

studies

0.69

confidence

25

Bdb 2 3r 1 Adamantan 2 Yl Carbamoyl 7 Bromo 2 3 Dihydrospiro Indene 1 4 Piperidine 3

2

studies

0.69

confidence

26

Bdb 2 3s 1 Adamantan 2 Yl Carbamoyl 7 Bromo 2 3 Dihydrospiro Indene 1 4 Piperidine 3

2

studies

0.69

confidence

27

Bdb 2 Hexahydro 2 5 Methanopentalen 3a 1h Ylamino 1 Thia 3 Azaspiro 4 4 Non 2 En 4 O

2

studies

0.69

confidence

28

Bdb 3 3 Dimethyl 1 5 1h Tetrazol 5 Yl Adamantan 2 Yl 4 5 Trifluoromethyl Pyridin 2 Y

2

studies

0.69

confidence

29

Bdb 3 3 Dimethyl Pentanedioic Acid 5 Carbamoyl Adamantan 2 Yl Amide Cyclopropylamide

2

studies

0.69

confidence

30

Bdb 3 3 Dimethyl Pentanedioic Acid Cyclopropylamide 5 Hydroxy Adamantan 2 Yl Amide C

2

studies

0.69

confidence

31

Bdb 3 Adamantan 1 Yl 5 6 7 8 9 10 Hexahydro 1 2 4 Triazolo 4 3 A Azocine Chembl25677

2

studies

0.69

confidence

32

Bdb 3 Benzyl 1 5 Hydroxy Adamantan 2 Yl Pyrrolidin 2 One Chembl376306

2

studies

0.69

confidence

33

Bdb 3 Phenyl Adamantan 1 Yl Piperidin 1 Yl Methanone Chembl1088379

2

studies

0.69

confidence

34

Bdb 4 1 4 5 Trifluoromethyl Pyridin 2 Yl Piperazin 1 Yl Cyclopropanecarbonyl Amino A

2

studies

0.69

confidence

35

Bdb 4 2 3 3 Difluoro Piperidin 1 Yl Butyrylamino Adamantane 1 Carboxylic Acid Amide

2

studies

0.69

confidence

36

Bdb 4 2 Methyl 2 4 5 Trifluoromethyl Pyridin 2 Yl Piperazin 1 Yl Propionylamino Adam

2

studies

0.69

confidence

37

Bdb 4 3 3 Dimethyl 2 Oxo 4 4 1 2 4 Triazol 1 Yl Phenoxymethyl Pyrrolidin 1 Yl Adaman

2

studies

0.69

confidence

38

Bdb 4 4 4 Imidazol 1 Yl Phenoxymethyl 3 3 Dimethyl 2 Oxo Pyrrolidin 1 Yl Adamantane

2

studies

0.69

confidence

39

Bdb 4 Amino 3 5 Dichloro Phenyl 2 Aza Tricyclo 3 3 1 1 3 7 Dec 2 Yl Methanone Chembl

2

studies

0.69

confidence

40

Bdb 5 5 Diethyl 2 Tricyclo 3 3 1 0 3 7 Nonan 3 Ylamino 4 5 Dihydro 1 3 Thiazol 4 One

2

studies

0.69

confidence

41

Bdb 5 Ethyl 5 Methyl 2 Tricyclo 3 3 1 0 3 7 Nonan 3 Ylamino 4 5 Dihydro 1 3 Thiazol

2

studies

0.69

confidence

42

Bdb Chembl2152223

2

studies

0.69

confidence

43

Bdb Chembl2152237

2

studies

0.69

confidence

44

Bdb Chembl2380648

2

studies

0.69

confidence

45

Bdb Chembl3401671

2

studies

0.69

confidence

46

Bdb Chembl3401681

2

studies

0.69

confidence

47

Bdb Chembl3401685

2

studies

0.69

confidence

48

Bdb Chembl4160328

2

studies

0.69

confidence

49

Bdb Chembl4162610

2

studies

0.69

confidence

50

Bdb Chembl4163698

2

studies

0.69

confidence

Top 50 compounds by confidence score. Derived from BindingDB assay data.

Data Source

Corpusv20260307-01

SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.