BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGET

MAP4K5

mitogen-activated protein kinase kinase kinase kinase 5

57 compounds · BiohacksAI corpus v20260307-01

57
compounds
Compounds
57
Gene Symbol
MAP4K5
NCBI Gene
11183

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About MAP4K5

MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 57 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting MAP4K5 (50)
1
Foretinib
4.34
confidence
2
Tozasertib
4.33
confidence
3
Vandetanib
4.30
confidence
4
Bosutinib
4.08
confidence
5
Quizartinib
3.99
confidence
6
Midostaurin
3.85
confidence
7
Pazopanib
3.69
confidence
8
Neratinib
3.66
confidence
9
Nintedanib
3.61
confidence
10
Canertinib
3.53
confidence
11
Pelitinib
3.50
confidence
12
Tae 684
3.43
confidence
13
Gilteritinib
3.40
confidence
14
Linifanib
3.33
confidence
15
Saracatinib
3.33
confidence
16
Tandutinib
3.22
confidence
17
Dovitinib
3.09
confidence
18
Jnj 7706621
3.09
confidence
19
At 9283
3.09
confidence
20
Lestaurtinib
3.04
confidence
21
Lenvatinib
3.04
confidence
22
Ruboxistaurin
2.94
confidence
23
Danusertib
2.94
confidence
24
Defosbarasertib
2.89
confidence
25
Barasertib
2.89
confidence
26
K 252a
2.83
confidence
27
Cediranib
2.83
confidence
28
Imd 0354
2.83
confidence
29
Milciclib
2.77
confidence
30
Pha 665752
2.71
confidence
31
Plx 4720
2.71
confidence
32
Crenolanib
2.71
confidence
33
Enmd 2076
2.71
confidence
34
Kw 2449
2.64
confidence
35
Linsitinib
2.64
confidence
36
Ast 487
2.56
confidence
37
Zotiraciclib
2.56
confidence
38
Raf 265
2.48
confidence
39
Brivanib
2.48
confidence
40
Azd 7762
2.30
confidence
41
Aee 788
2.30
confidence
42
Su 014813
2.20
confidence
43
Rebastinib
2.20
confidence
44
Golvatinib
2.20
confidence
45
Cyc 116
2.08
confidence
46
Amg 900
2.08
confidence
47
Ly 3009120
2.08
confidence
300
studies
1.95
confidence
49
Cep 32496
1.95
confidence
50
Pf 03814735
1.79
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.