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BiohacksAI/Targets/MAPK8
MOLECULAR TARGETUniProt: P45983

MAPK8

mitogen-activated protein kinase 8

48 compounds · BiohacksAI corpus v20260307-01

48
compounds
Compounds
48
Gene Symbol
MAPK8
NCBI Gene
5599

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About MAPK8

MAPK8 (mitogen-activated protein kinase 8) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 48 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View MAPK8 on UniProt →
Compounds Targeting MAPK8 (48)
1
Imatinib
5.47
confidence
2
Sb 203580
4.92
confidence
3
Alvocidib
4.52
confidence
4
Foretinib
4.34
confidence
5
Ruxolitinib
4.23
confidence
6
Nilotinib
4.17
confidence
7
Doramapimod
4.06
confidence
8
Midostaurin
3.85
confidence
9
Pazopanib
3.69
confidence
10
Neratinib
3.66
confidence
11
Abemaciclib
3.66
confidence
12
Sb 202190
3.64
confidence
13
Nintedanib
3.61
confidence
14
Tryptanthrin
3.47
confidence
15
Tae 684
3.43
confidence
16
Fedratinib
3.40
confidence
17
Gilteritinib
3.40
confidence
18
Sp 600125
3.22
confidence
19
Jnj 7706621
3.09
confidence
20
At 9283
3.09
confidence
21
Lestaurtinib
3.04
confidence
22
Pacritinib
3.04
confidence
23
Sp600125
117
studies
2.94
confidence
24
Momelotinib
2.89
confidence
25
R 406
2.83
confidence
26
K 252a
2.83
confidence
27
Azd 5438
2.71
confidence
28
Kw 2449
2.64
confidence
29
Ast 487
2.56
confidence
30
Zotiraciclib
2.56
confidence
31
Mk 5108
2.48
confidence
32
Sgx 523
2.30
confidence
33
Rebastinib
2.20
confidence
34
Encorafenib
2.20
confidence
35
Cyc 116
2.08
confidence
36
Fostamatinib
2.08
confidence
37
Zemirciclib
2.08
confidence
38
Cep 32496
1.95
confidence
39
Tanzisertib
1.95
confidence
40
Anisomycin
247
studies
1.10
confidence
41
Pictilisibdrugage
0
studies
1.10
confidence
42
Bufo Bufo
1.00
confidence
43
Axitinib
298
studies
0.69
confidence
44
Cardamonin
180
studies
0.69
confidence
45
Hesperetin
300
studies
0.69
confidence
46
Citrus Reticulata
0.50
confidence
47
Paeonia Lactiflora
0.50
confidence
48
Pulsatilla Chinensis
0.50
confidence
Top 48 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.