BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGET

MARK2

microtubule affinity regulating kinase 2

42 compounds · BiohacksAI corpus v20260307-01

42
compounds
Compounds
42
Gene Symbol
MARK2
NCBI Gene
2011

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About MARK2

MARK2 (microtubule affinity regulating kinase 2) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 42 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting MARK2 (42)
1
Tofacitinib
4.65
confidence
2
Tozasertib
4.33
confidence
3
Ruxolitinib
4.23
confidence
4
Doramapimod
4.06
confidence
5
Midostaurin
3.85
confidence
6
Brigatinib
3.81
confidence
7
Silmitasertib
3.78
confidence
8
Nintedanib
3.61
confidence
9
Baricitinib
3.56
confidence
10
Tae 684
3.43
confidence
11
Fedratinib
3.40
confidence
12
Sp 600125
3.22
confidence
13
Dovitinib
3.09
confidence
14
Jnj 7706621
3.09
confidence
15
At 9283
3.09
confidence
16
Lestaurtinib
3.04
confidence
17
Pf 03758309
3.00
confidence
18
Ruboxistaurin
2.94
confidence
19
Danusertib
2.94
confidence
20
Momelotinib
2.89
confidence
21
R 406
2.83
confidence
22
K 252a
2.83
confidence
23
Milciclib
2.77
confidence
24
Pf 00562271
2.77
confidence
25
Pha 665752
2.71
confidence
26
Crenolanib
2.71
confidence
27
Kw 2449
2.64
confidence
28
Gsk 690693
2.64
confidence
29
Defactinib
2.48
confidence
30
Ripasudil
2.40
confidence
31
Azd 7762
2.30
confidence
32
Bms 754807
2.30
confidence
33
Su 014813
2.20
confidence
34
Decernotinib
2.20
confidence
35
Cyc 116
2.08
confidence
36
Uprosertib
1.95
confidence
37
Cerdulatinib
1.95
confidence
38
Pf 03814735
1.79
confidence
39
Ucn 01
1.79
confidence
12
studies
0.69
confidence
8
studies
0.69
confidence
117
studies
0.69
confidence
Top 42 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.