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BiohacksAI/Targets/MCL1
MOLECULAR TARGETUniProt: AAF64255

MCL1

MCL1 apoptosis regulator, BCL2 family member

165 compounds · BiohacksAI corpus v20260307-01

165
compounds
Compounds
165
Gene Symbol
MCL1
NCBI Gene
4170

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About MCL1

MCL1 (MCL1 apoptosis regulator, BCL2 family member) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 165 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View MCL1 on UniProt →
Compounds Targeting MCL1 (50)
1
Gossypol
4.42
confidence
2
Umbelliferone
4.42
confidence
3
Coumarin
4.23
confidence
4
Scopoletin
4.16
confidence
5
Abt 737
4.04
confidence
6
Gambogic Acid
3.69
confidence
7
Esculetin
3.64
confidence
8
Hymecromone
3.61
confidence
9
Navitoclax
3.53
confidence
10
Athraquinones A
3.14
confidence
11
Daphnetin
2.94
confidence
12
6 Hydroxycoumarin
2.56
confidence
13
Fraxetin
2.56
confidence
14
Isoscopoletin
2.48
confidence
15
Isokaempferide
2.30
confidence
16
4 Methylesculetin
2.30
confidence
17
Azd 5991
2.20
confidence
18
Obatoclax
2.08
confidence
19
Asterric Acid
1.95
confidence
20
Tapotoclax
1.95
confidence
21
Acenaphthoquinone
1.79
confidence
22
Apogossypol
1.79
confidence
23
Methysergide Maleate
1.79
confidence
24
Alpha Lipoic Acid
169
studies
1.61
confidence
25
Hexachlorophene
300
studies
1.61
confidence
26
Thioctic Acid
300
studies
1.61
confidence
27
Ala
169
studies
1.61
confidence
28
Oxytetracycline
300
studies
1.39
confidence
29
Egcg
300
studies
1.10
confidence
30
Rosmarinic Acid
300
studies
1.10
confidence
31
Paxilline
42
studies
1.10
confidence
32
Cuscuta Chinensis
1.00
confidence
33
Allium Tuberosum
1.00
confidence
34
Aloe Vera
1.00
confidence
35
Anemarrhena Asphodeloides
1.00
confidence
36
Arctium Lappa
1.00
confidence
37
Artemisia Annua
1.00
confidence
38
Artemisia Capillaris
1.00
confidence
39
Aster Tataricus
1.00
confidence
40
Atractylodes Macrocephala
1.00
confidence
41
Bombyx Mori
1.00
confidence
42
Bupleurum Chinense
1.00
confidence
43
Carthamus Tinctorius
1.00
confidence
44
Centella Asiatica
499
studies
1.00
confidence
45
Chaenomeles Speciosa
1.00
confidence
46
Cimicifuga Heracleifolia
1.00
confidence
47
Citrus Reticulata
1.00
confidence
48
Curcuma Longa
500
studies
1.00
confidence
49
Agastache Rugosa
1.00
confidence
50
Allium Sativum
500
studies
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.