MOLECULAR TARGETUniProt: O75116
ROCK2
Rho associated coiled-coil containing protein kinase 2
48 compounds · BiohacksAI corpus v20260307-01
48
compounds
Compounds
48
Gene Symbol
ROCK2
NCBI Gene
9475
Looking for compounds that interact with ROCK2?
View all 48 compounds →About ROCK2
ROCK2 (Rho associated coiled-coil containing protein kinase 2) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 48 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.
View ROCK2 on UniProt →Compounds Targeting ROCK2 (48)
1
Tofacitinib
4.65
confidence
2
Alvocidib
4.52
confidence
3
Foretinib
4.34
confidence
4
Vandetanib
4.30
confidence
5
Ruxolitinib
4.23
confidence
6
Ceritinib
4.19
confidence
7
Bosutinib
4.08
confidence
8
Midostaurin
3.85
confidence
9
Fasudil
3.66
confidence
10
Baricitinib
3.56
confidence
11
Y 27632
3.47
confidence
12
Tae 684
3.43
confidence
13
Fedratinib
3.40
confidence
14
Linifanib
3.33
confidence
15
11
studies
3.30
confidence
16
Dovitinib
3.09
confidence
17
Upadacitinib
3.09
confidence
18
Lestaurtinib
3.04
confidence
19
Momelotinib
2.89
confidence
20
R 406
2.83
confidence
21
Capivasertib
2.77
confidence
22
Pha 665752
2.71
confidence
23
Kw 2449
2.64
confidence
24
Gsk 690693
2.64
confidence
25
Ast 487
2.56
confidence
26
Zotiraciclib
2.56
confidence
27
Ripasudil
2.40
confidence
28
Hydroxyfasudil
2.40
confidence
29
Belumosudil
2.30
confidence
30
Su 014813
2.20
confidence
31
Gsk 1070916
2.20
confidence
32
Decernotinib
2.20
confidence
33
Y 39983
2.20
confidence
34
Cyc 116
2.08
confidence
35
Rg 547
2.08
confidence
36
Gsk 269962a
2.08
confidence
37
Uprosertib
1.95
confidence
38
Lx 7101
1.95
confidence
39
Netarsudil
1.95
confidence
40
Ucn 01
1.79
confidence
41
Afuresertib
1.79
confidence
42
Sar 407899 Free Base
1.79
confidence
8
studies
1.10
confidence
44
300
studies
0.69
confidence
12
studies
0.69
confidence
298
studies
0.69
confidence
298
studies
0.69
confidence
48
117
studies
0.69
confidence
Top 48 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed
All data is computationally derived from published research. Not medical advice. Independent validation required.