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BiohacksAI/Targets/ROCK2
MOLECULAR TARGETUniProt: O75116

ROCK2

Rho associated coiled-coil containing protein kinase 2

162 compounds · BiohacksAI corpus v20260307-01

162
compounds
Compounds
162
Gene Symbol
ROCK2
NCBI Gene
9475

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About ROCK2

ROCK2 (Rho associated coiled-coil containing protein kinase 2) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 162 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View ROCK2 on UniProt →
Compounds Targeting ROCK2 (50)
1
Tofacitinib
4.65
confidence
2
Alvocidib
4.52
confidence
3
Foretinib
4.34
confidence
4
Vandetanib
4.30
confidence
5
Ruxolitinib
4.23
confidence
6
Ceritinib
4.19
confidence
7
Bosutinib
4.08
confidence
8
Midostaurin
3.85
confidence
9
Fasudil
3.66
confidence
10
Baricitinib
3.56
confidence
11
Y 27632
3.47
confidence
12
Tae 684
3.43
confidence
13
Fedratinib
3.40
confidence
14
Linifanib
3.33
confidence
15
Ha1077
11
studies
3.30
confidence
16
Upadacitinib
3.09
confidence
17
Dovitinib
3.09
confidence
18
Lestaurtinib
3.04
confidence
19
Momelotinib
2.89
confidence
20
R 406
2.83
confidence
21
Capivasertib
2.77
confidence
22
Pha 665752
2.71
confidence
23
Kw 2449
2.64
confidence
24
Gsk 690693
2.64
confidence
25
Ast 487
2.56
confidence
26
Zotiraciclib
2.56
confidence
27
Hydroxyfasudil
2.40
confidence
28
Ripasudil
2.40
confidence
29
Belumosudil
2.30
confidence
30
Gsk 1070916
2.20
confidence
31
Y 39983
2.20
confidence
32
Su 014813
2.20
confidence
33
Decernotinib
2.20
confidence
34
Gsk 269962a
2.08
confidence
35
Cyc 116
2.08
confidence
36
Rg 547
2.08
confidence
37
Lx 7101
1.95
confidence
38
Uprosertib
1.95
confidence
39
Netarsudil
1.95
confidence
40
Afuresertib
1.79
confidence
41
Ucn 01
1.79
confidence
42
Sar 407899 Free Base
1.79
confidence
43
Kenpaullone
8
studies
1.10
confidence
44
Allium Tuberosum
1.00
confidence
45
Anemarrhena Asphodeloides
1.00
confidence
46
Arctium Lappa
1.00
confidence
47
Artemisia Argyi
1.00
confidence
48
Artemisia Capillaris
1.00
confidence
49
Allium Sativum
500
studies
1.00
confidence
50
Aloe Vera
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.