What compounds target CA6?

BiohacksAI has identified 31 compounds that interact with CA6 (carbonic anhydrase 6). Top compounds include: Zonisamide, Sulfanilamide, Indapamide, benzolamide, Mafenide. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CA6 (carbonic anhydrase 6)?

CA6 is carbonic anhydrase 6. It is a molecular target for 31 compounds documented in PubMed bioassay data. UniProt ID: P23280. NCBI Gene ID: 765.

CA6

MOLECULAR TARGET

carbonic anhydrase 6

UniProt: P23280 NCBI Gene: 76531 compounds

CA6 (carbonic anhydrase 6) is targeted by 31 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CA6

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Zonisamide	2.48	11
2	Sulfanilamide	2.20	8
3	Indapamide	2.08	7
4	benzolamide	1.95	6
5	Mafenide	1.79	5
6	Celecoxib	1.61	4
7	Chlorthalidone	1.61	4
8	Sulpiride	1.61	4
9	Furosemide	1.39	3
10	Histamine	1.39	3
11	Tyrosine	1.10	2
12	Tyrosine	1.10	2
13	Bumetanide	1.10	2
14	Metolazone	1.10	2
15	4-Hydroxybenzoate-3-Monooxygenase	1.10	2
16	stx64	1.10	2
17	caffeic acid	0.69	1
18	Catechin	0.69	1
19	Histidine	0.69	1
20	Quercetin	0.69	1
21	Resveratrol	0.69	1
22	Spermidine	0.69	1
23	Bortezomib	0.69	1
24	Catechin	0.69	1
25	Famotidine	0.69	1
26	Vanillic Acid	0.69	1
27	Secologanin Tryptamine Alkaloids Compounds formed by condensation of secologanin with tryptamine resulting in	0.69	1
28	Lacosamide	0.69	1
29	Sildenafil Citrate	0.69	1
30	Spermine	0.69	1
31	thiamine	0.69	1

About CA6 as a Drug Target

CA6 (carbonic anhydrase 6) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 31 compounds with documented CA6 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CA6 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.