CACNA1C
MOLECULAR TARGETcalcium voltage-gated channel subunit alpha1 C
CACNA1C (calcium voltage-gated channel subunit alpha1 C) is targeted by 24 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CACNA1C
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Nitrendipine | 2.40 | 10 |
| 2 | Amlodipine | 1.79 | 5 |
| 3 | Nisoldipine | 1.79 | 5 |
| 4 | Fluoxetine | 1.39 | 3 |
| 5 | Sertraline | 1.39 | 3 |
| 6 | Quinidine | 1.39 | 3 |
| 7 | Arachidonic Acid | 1.10 | 2 |
| 8 | Testosterone | 1.10 | 2 |
| 9 | Fluspirilene | 1.10 | 2 |
| 10 | cbd | 0.69 | 1 |
| 11 | Duloxetine Hydrochloride | 0.69 | 1 |
| 12 | Adapalene | 0.69 | 1 |
| 13 | Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent | 0.69 | 1 |
| 14 | Astemizole Antihistamine drug now withdrawn from | 0.69 | 1 |
| 15 | cannabidiol | 0.69 | 1 |
| 16 | cgp37157 | 0.69 | 1 |
| 17 | Clotrimazole | 0.69 | 1 |
| 18 | Crizotinib | 0.69 | 1 |
| 19 | Doripenem | 0.69 | 1 |
| 20 | Miconazole | 0.69 | 1 |
| 21 | Reserpine | 0.69 | 1 |
| 22 | Rimonabant | 0.69 | 1 |
| 23 | Troglitazone | 0.69 | 1 |
| 24 | Yohimbine | 0.69 | 1 |
About CACNA1C as a Drug Target
CACNA1C (calcium voltage-gated channel subunit alpha1 C) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 24 compounds with documented CACNA1C interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CACNA1C inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.