BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Yohimbine

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.

299+ PubMed studies analyzed · 35 RCTs · Evidence Score: 47.8

Research Domains

Yohimbine has been studied across 20 research domains including 🧠 Focus & Attention, 🧘 Stress & Anxiety, 🌤️ Mood & Depression, ❤️ Cardiovascular, 🔥 Metabolic. The primary research focus is 🧠 Focus & Attention with 24% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Yohimbine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Dihydroergotamine
30 shared targets
Lisuride
28 shared targets
Pergolide
28 shared targets
Ergotamine
25 shared targets
Oxymetazoline
20 shared targets
Bromocriptine
29 shared targets
Buspirone
25 shared targets
Quetiapine
26 shared targets
Phentolamine
21 shared targets
Trazodone
21 shared targets
Loading evidence profile...

This evidence profile for Yohimbine is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.