What compounds target ESTROGEN?

BiohacksAI has identified 21 compounds that interact with ESTROGEN (Estrogen receptor (human)). Top compounds include: Fulvestrant, Estrone, Ethinyl Estradiol, Estriol, Androstenediol. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ESTROGEN (Estrogen receptor (human))?

ESTROGEN is Estrogen receptor (human). It is a molecular target for 21 compounds documented in PubMed bioassay data. UniProt ID: P03372.

ESTROGEN

MOLECULAR TARGET

Estrogen receptor (human)

UniProt: P0337221 compounds

ESTROGEN (Estrogen receptor (human)) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ESTROGEN

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Fulvestrant	4.57	96
2	Estrone	2.89	17
3	Ethinyl Estradiol	2.08	7
4	Estriol	1.79	5
5	Androstenediol	1.61	4
6	Estetrol	1.39	3
7	Medroxyprogesterone Acetate	1.39	3
8	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	1.10	2
9	Ethylestrenol	1.10	2
10	Mestranol	1.10	2
11	Norethindrone	1.10	2
12	Stanozolol	1.10	2
13	trichostatic acid [Supplementary Concept] related to trichostatin	1.10	2
14	Progesterone	0.69	1
15	Resveratrol	0.69	1
16	Testosterone	0.69	1
17	candesartan cilexetil [Supplementary Concept]	0.69	1
18	Cephacetrile	0.69	1
19	Danazol	0.69	1
20	Daunorubicin	0.69	1
21	Spironolactone	0.69	1

About ESTROGEN as a Drug Target

ESTROGEN (Estrogen receptor (human)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented ESTROGEN interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ESTROGEN inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.