A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.
Estriol has been studied across 19 research domains including 🧬 Hormones, 😴 Sleep, 🔬 Oncology, 🧠 Focus & Attention, 🧘 Stress & Anxiety. The primary research focus is 🧬 Hormones with 46% of studies addressing this area.
The following compounds share molecular targets with Estriol, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Estriol is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.