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Androstenediol

An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).

300+ PubMed studies analyzed · 9 RCTs · Evidence Score: 46

Research Domains

Androstenediol has been studied across 23 research domains including 🧬 Hormones, 💪 Strength & Power, ♀♂ Sexual Health, 🔬 Oncology, 🫘 Kidney. The primary research focus is 🧬 Hormones with 45% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Androstenediol, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Estriol
7 shared targets
stanolone
4 shared targets
Estetrol
2 shared targets
Pregnenolone
6 shared targets
Allylestrenol
3 shared targets
Metipranolol
3 shared targets
Nandrolone
6 shared targets
brilanestrant
3 shared targets
cortodoxone
2 shared targets
hydroxyprogesterone
3 shared targets
Loading evidence profile...

This evidence profile for Androstenediol is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.