What compounds target FOS?

BiohacksAI has identified 123 compounds that interact with FOS (Fos proto-oncogene, AP-1 transcription factor subunit). Top compounds include: agastache rugosa, Garlic, allium tuberosum, aloe vera, apis mellifera. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is FOS (Fos proto-oncogene, AP-1)?

FOS is Fos proto-oncogene, AP-1 transcription factor subunit. It is a molecular target for 123 compounds documented in PubMed bioassay data. UniProt ID: P01100. NCBI Gene ID: 2353.

FOS

MOLECULAR TARGET

Fos proto-oncogene, AP-1 transcription factor subunit

UniProt: P01100 NCBI Gene: 2353123 compounds

FOS (Fos proto-oncogene, AP-1 transcription factor subunit) is targeted by 123 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting FOS

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	agastache rugosa	1.00	1
2	Garlic	1.00	1
3	allium tuberosum	1.00	1
4	aloe vera	1.00	1
5	apis mellifera	1.00	1
6	arctium lappa	1.00	1
7	artemisia argyi	1.00	1
8	artemisia capillaris	1.00	1
9	atractylodes macrocephala	1.00	1
10	bufo bufo	1.00	1
11	bupleurum chinense	1.00	1
12	carthamus tinctorius	1.00	1
13	Centella	1.00	1
14	chaenomeles speciosa	1.00	1
15	citrus reticulata	1.00	1
16	cnidium monnieri	1.00	1
17	curculigo orchioides	1.00	1
18	Curcuma	1.00	1
19	cynomorium songaricum	1.00	1
20	ephedra sinica	1.00	1
21	eucommia ulmoides	1.00	1
22	Foeniculum	1.00	1
23	forsythia suspensa	1.00	1
24	fritillaria cirrhosa	1.00	1
25	gastrodia elata	1.00	1
26	Ginkgo biloba	1.00	1
27	glycine max	1.00	1
28	glycyrrhiza uralensis	1.00	1
29	ligusticum chuanxiong	1.00	1
30	lilium lancifolium	1.00	1
31	litchi chinensis	1.00	1
32	lithospermum erythrorhizon	1.00	1
33	lobelia chinensis	1.00	1
34	lonicera japonica	1.00	1
35	magnolia biondii	1.00	1
36	morus alba	1.00	1
37	Nelumbo	1.00	1
38	Panax	1.00	1
39	panax notoginseng	1.00	1
40	perilla frutescens	1.00	1
41	pinellia ternata	1.00	1
42	polygonum cuspidatum	1.00	1
43	poria cocos	1.00	1
44	Portulaca	1.00	1
45	prunella vulgaris	1.00	1
46	prunus armeniaca	1.00	1
47	quisqualis indica	1.00	1
48	rehmannia glutinosa	1.00	1
49	Rubia	1.00	1
50	salvia miltiorrhiza	1.00	1

Showing top 50 of 123 compounds. Use the BiohacksAI search to explore all FOS modulators.

About FOS as a Drug Target

FOS (Fos proto-oncogene, AP-1 transcription factor subunit) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 123 compounds with documented FOS interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

FOS inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.