Kelch-like ECH-associated protein 1
KEAP1 (Kelch-like ECH-associated protein 1) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | bardoxolone | 3.00 | 19 |
| 2 | Resveratrol | 2.30 | 9 |
| 3 | alyssin [Supplementary Concept] | 1.79 | 5 |
| 4 | Fusaric Acid | 0.69 | 1 |
| 5 | artemisia annua | 0.50 | 1 |
| 6 | panax notoginseng | 0.50 | 1 |
| 7 | salvia miltiorrhiza | 0.50 | 1 |
KEAP1 (Kelch-like ECH-associated protein 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented KEAP1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
KEAP1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.