What compounds target MAPK7?

BiohacksAI has identified 134 compounds that interact with MAPK7 (mitogen-activated protein kinase 7). Top compounds include: alvocidib, tozasertib, ceritinib, bosutinib, bi 2536. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is MAPK7 (mitogen-activated protein kinase)?

MAPK7 is mitogen-activated protein kinase 7. It is a molecular target for 134 compounds documented in PubMed bioassay data. UniProt ID: Q13164. NCBI Gene ID: 5598.

MAPK7

MOLECULAR TARGET

mitogen-activated protein kinase 7

UniProt: Q13164 NCBI Gene: 5598134 compounds

MAPK7 (mitogen-activated protein kinase 7) is targeted by 134 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting MAPK7

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	alvocidib	4.52	91
2	tozasertib	4.33	75
3	ceritinib	4.19	65
4	bosutinib	4.08	58
5	bi 2536	4.01	54
6	nintedanib	3.61	36
7	bms 387032	3.47	31
8	tae 684	3.43	30
9	fedratinib	3.40	29
10	at 7519	3.33	27
11	jnj 7706621	3.09	21
12	lestaurtinib	3.04	20
13	pf 03758309	3.00	19
14	danusertib	2.94	18
15	pf 00562271	2.77	15
16	pha 665752	2.71	14
17	bms 345541	2.71	14
18	kw 2449	2.64	13
19	zotiraciclib	2.56	12
20	rg 547	2.08	7
21	pf 03814735	1.79	5
22	achyranthes bidentata	1.00	1
23	agastache rugosa	1.00	1
24	Garlic	1.00	1
25	allium tuberosum	1.00	1
26	aloe vera	1.00	1
27	arctium lappa	1.00	1
28	artemisia capillaris	1.00	1
29	aster tataricus	1.00	1
30	bombyx mori	1.00	1
31	Centella	1.00	1
32	citrus reticulata	1.00	1
33	Curcuma	1.00	1
34	cynomorium songaricum	1.00	1
35	ephedra sinica	1.00	1
36	eriobotrya japonica	1.00	1
37	eucommia ulmoides	1.00	1
38	forsythia suspensa	1.00	1
39	fritillaria cirrhosa	1.00	1
40	gastrodia elata	1.00	1
41	Ginkgo biloba	1.00	1
42	glycine max	1.00	1
43	lilium lancifolium	1.00	1
44	litchi chinensis	1.00	1
45	lithospermum erythrorhizon	1.00	1
46	lobelia chinensis	1.00	1
47	lonicera japonica	1.00	1
48	morus alba	1.00	1
49	Nelumbo	1.00	1
50	paeonia lactiflora	1.00	1

Showing top 50 of 134 compounds. Use the BiohacksAI search to explore all MAPK7 modulators.

About MAPK7 as a Drug Target

MAPK7 (mitogen-activated protein kinase 7) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 134 compounds with documented MAPK7 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

MAPK7 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.