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Compounds That Target AKR1B1

aldo-keto reductase family 1 member B1 · 172 compounds in BiohacksAI corpus

AKR1B1 (aldo-keto reductase family 1 member B1) is a biological target with 172 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into AKR1B1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for AKR1B1
500+
studies
300+
studies
300+
studies
300+
studies
300+
studies
300+
studies
199+
studies
150+
studies
All 50 Compounds — Ranked by Evidence
1
Betulinic Acid
5.21
confidence
2
Isoliquiritigenin
4.50
confidence
3
Isoquercetin
4.50
confidence
4
Coumaric Acid
4.42
confidence
5
Gossypol
4.42
confidence
6
Umbelliferone
4.42
confidence
7
Sorbinil
4.26
confidence
8
Caffeic Acid Phenethyl Ester
4.25
confidence
9
Scopoletin
4.16
confidence
10
Flufenamic Acid
4.14
confidence
11
7 Hydroxyflavone
4.01
confidence
12
Epalrestat
4.01
confidence
13
Quercitrin
3.97
confidence
14
Nitazoxanide
3.97
confidence
15
Mefenamic Acid
3.93
confidence
16
Maslinic Acid
3.89
confidence
17
Bisdemethoxycurcumin
3.78
confidence
18
Tanshinone Iia
3.74
confidence
19
Astragalin
3.74
confidence
20
Tolrestat
3.69
confidence
21
Esculetin
3.64
confidence
22
Hymecromone
3.61
confidence
23
Hyperoside
3.56
confidence
24
Asiatic Acid
3.47
confidence
25
Rhamnetin
3.33
confidence
26
Herniarin
3.04
confidence
27
Zopolrestat
3.04
confidence
28
3 Hydroxycoumarin
2.94
confidence
29
Erythrodiol
2.94
confidence
300+
studies
2.71
confidence
31
Benzyl Caffeate
2.71
confidence
32
Isoscopoletin
2.48
confidence
33
Tricin
2.40
confidence
34
Drupanin
2.30
confidence
35
4 Methylesculetin
2.30
confidence
36
Phenethyl Cinnamate
2.30
confidence
37
Artepillin
2.20
confidence
38
Minalrestat
1.79
confidence
300+
studies
1.61
confidence
300+
studies
1.39
confidence
150+
studies
1.39
confidence
42
Chrysinflavonoids
1.10
confidence
300+
studies
1.10
confidence
300+
studies
1.10
confidence
45
Achyranthes Bidentata
1.00
confidence
46
Agastache Rugosa
1.00
confidence
500+
studies
1.00
confidence
48
Aloe Vera
1.00
confidence
49
Arctium Lappa
1.00
confidence
199+
studies
1.00
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for AKR1B1 (aldo-keto reductase family 1 member B1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: AKR1B1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.