BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target BRAF

B-Raf proto-oncogene, serine/threonine kinase · 67 compounds in BiohacksAI corpus

BRAF (B-Raf proto-oncogene, serine/threonine kinase) is a biological target with 67 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into BRAF modulation for therapeutic and biohacking applications.

Most Studied Compounds for BRAF
500+
studies
499+
studies
300+
studies
300+
studies
299+
studies
298+
studies
All 52 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Erlotinib
5.55
confidence
3
Imatinib
5.47
confidence
4
Sb 203580
4.92
confidence
300+
studies
4.48
confidence
6
Foretinib
4.34
confidence
298+
studies
4.33
confidence
8
Ponatinib
4.26
confidence
9
Ruxolitinib
4.23
confidence
10
Pi 103
4.17
confidence
11
Nilotinib
4.17
confidence
12
Doramapimod
4.06
confidence
13
Pazopanib
3.69
confidence
14
Abemaciclib
3.66
confidence
15
Sb 202190
3.64
confidence
16
Regorafenib
3.56
confidence
17
Bms 387032
3.47
confidence
18
Fedratinib
3.40
confidence
19
Dabrafenib
3.30
confidence
20
Mirdametinib
3.18
confidence
21
Gw305074x
3.14
confidence
22
Dasatinib Anhydrous
3.09
confidence
23
R 406
2.83
confidence
24
Masitinib
2.77
confidence
25
Infigratinib
2.77
confidence
26
Plx 4720
2.71
confidence
27
Cobimetinib
2.64
confidence
28
Ast 487
2.56
confidence
29
Motesanib
2.48
confidence
30
Raf 265
2.48
confidence
31
Sb590885
2.40
confidence
32
Avutometinib
2.30
confidence
33
Encorafenib
2.20
confidence
34
Rebastinib
2.20
confidence
35
Tg100 115
2.08
confidence
36
Ly 3009120
2.08
confidence
37
Amg 900
2.08
confidence
38
Bastadin 7
1.95
confidence
39
Naporafenib
1.95
confidence
40
Cep 32496
1.95
confidence
41
Bafetinib
1.95
confidence
42
Maleimide
1.95
confidence
299+
studies
1.10
confidence
500+
studies
1.00
confidence
45
Dimocarpus Longan
1.00
confidence
46
Morus Alba
1.00
confidence
47
Arctium Lappa
1.00
confidence
48
Artemisia Annua
1.00
confidence
49
Atractylodes Macrocephala
1.00
confidence
499+
studies
1.00
confidence
51
Myricetinflavonoids
0.69
confidence
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for BRAF (B-Raf proto-oncogene, serine/threonine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: BRAF target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.