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Compounds That Target BTK

Bruton tyrosine kinase · 50 compounds in BiohacksAI corpus

BTK (Bruton tyrosine kinase) is a biological target with 50 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into BTK modulation for therapeutic and biohacking applications.

Most Studied Compounds for BTK
All 50 Compounds — Ranked by Evidence
1
Osimertinib
5.03
confidence
2
Ibrutinib
4.86
confidence
3
Foretinib
4.34
confidence
4
Tozasertib
4.33
confidence
5
Vandetanib
4.30
confidence
6
Ponatinib
4.26
confidence
7
Ceritinib
4.19
confidence
8
Bosutinib
4.08
confidence
9
Brigatinib
3.81
confidence
10
Neratinib
3.66
confidence
11
Nintedanib
3.61
confidence
12
Canertinib
3.53
confidence
13
Pelitinib
3.50
confidence
14
Tae 684
3.43
confidence
15
Fedratinib
3.40
confidence
16
Mln 8054
3.33
confidence
17
Saracatinib
3.33
confidence
18
Acalabrutinib
3.22
confidence
19
Rociletinib
3.18
confidence
20
Sulfuretin
3.14
confidence
21
At 9283
3.09
confidence
22
Lestaurtinib
3.04
confidence
23
Spebrutinib
3.04
confidence
24
Pf 03758309
3.00
confidence
25
Danusertib
2.94
confidence
26
Defosbarasertib
2.89
confidence
27
R 406
2.83
confidence
28
K 252a
2.83
confidence
29
Cediranib
2.83
confidence
30
Ritlecitinib
2.77
confidence
31
Apitolisib
2.71
confidence
32
Kw 2449
2.64
confidence
33
Zanubrutinib
2.56
confidence
34
Poziotinib
2.48
confidence
35
Evobrutinib
2.48
confidence
36
Entospletinib
2.48
confidence
37
Azd 7762
2.30
confidence
38
Bms 754807
2.30
confidence
39
Olmutinib
2.30
confidence
40
Su 014813
2.20
confidence
41
Rebastinib
2.20
confidence
42
Futibatinib
2.20
confidence
43
Asp 3026
2.08
confidence
44
Tirabrutinib
1.95
confidence
45
Ucn 01
1.79
confidence
46
Tolebrutinib
1.79
confidence
298+
studies
0.69
confidence
299+
studies
0.69
confidence
4+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for BTK (Bruton tyrosine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: BTK target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.