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Compounds That Target CHEK1

checkpoint kinase 1 · 34 compounds in BiohacksAI corpus

CHEK1 (checkpoint kinase 1) is a biological target with 34 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into CHEK1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for CHEK1
117+
studies
8+
studies
All 34 Compounds — Ranked by Evidence
1
Tozasertib
4.33
confidence
2
Bosutinib
4.08
confidence
3
Midostaurin
3.85
confidence
4
Brigatinib
3.81
confidence
5
Silmitasertib
3.78
confidence
6
Neratinib
3.66
confidence
7
Nintedanib
3.61
confidence
8
Pelitinib
3.50
confidence
9
Tae 684
3.43
confidence
10
Fedratinib
3.40
confidence
11
Dovitinib
3.09
confidence
12
At 9283
3.09
confidence
13
Lestaurtinib
3.04
confidence
14
Pf 03758309
3.00
confidence
15
Hymenialdisine
3.00
confidence
16
Ruboxistaurin
2.94
confidence
17
R 406
2.83
confidence
18
K 252a
2.83
confidence
19
Pd 0166285
2.83
confidence
20
Kw 2449
2.64
confidence
21
Isogranulatimide
2.56
confidence
22
Debromohymenialdisine
2.56
confidence
23
Doxantrazole
2.40
confidence
24
Azd 7762
2.30
confidence
25
Granulatimide
2.30
confidence
26
Su 014813
2.20
confidence
27
Prexasertib
2.08
confidence
28
Cerdulatinib
1.95
confidence
29
Sra 737
1.95
confidence
30
Pf 03814735
1.79
confidence
31
Ucn 01
1.79
confidence
32
Rabusertib
1.79
confidence
8+
studies
0.69
confidence
117+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CHEK1 (checkpoint kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CHEK1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.