BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGET

CHEK1

checkpoint kinase 1

34 compounds · BiohacksAI corpus v20260307-01

34
compounds
Compounds
34
Gene Symbol
CHEK1
NCBI Gene
1111

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About CHEK1

CHEK1 (checkpoint kinase 1) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 34 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting CHEK1 (34)
1
Tozasertib
4.33
confidence
2
Bosutinib
4.08
confidence
3
Midostaurin
3.85
confidence
4
Brigatinib
3.81
confidence
5
Silmitasertib
3.78
confidence
6
Neratinib
3.66
confidence
7
Nintedanib
3.61
confidence
8
Pelitinib
3.50
confidence
9
Tae 684
3.43
confidence
10
Fedratinib
3.40
confidence
11
Dovitinib
3.09
confidence
12
At 9283
3.09
confidence
13
Lestaurtinib
3.04
confidence
14
Pf 03758309
3.00
confidence
15
Hymenialdisine
3.00
confidence
16
Ruboxistaurin
2.94
confidence
17
R 406
2.83
confidence
18
K 252a
2.83
confidence
19
Pd 0166285
2.83
confidence
20
Kw 2449
2.64
confidence
21
Isogranulatimide
2.56
confidence
22
Debromohymenialdisine
2.56
confidence
23
Doxantrazole
2.40
confidence
24
Azd 7762
2.30
confidence
25
Granulatimide
2.30
confidence
26
Su 014813
2.20
confidence
27
Prexasertib
2.08
confidence
28
Cerdulatinib
1.95
confidence
29
Sra 737
1.95
confidence
30
Pf 03814735
1.79
confidence
31
Ucn 01
1.79
confidence
32
Rabusertib
1.79
confidence
8
studies
0.69
confidence
117
studies
0.69
confidence
Top 34 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.