Compounds That Target CHEK2

checkpoint kinase 2 · 138 compounds in BiohacksAI corpus

CHEK2 (checkpoint kinase 2) is a biological target with 138 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into CHEK2 modulation for therapeutic and biohacking applications.

View CHEK2 target page →UniProt: O96017 ↗

Most Studied Compounds for CHEK2

Allium Sativum

500+

studies

Curcuma Longa

500+

studies

Centella Asiatica

499+

studies

Lovastatin

300+

studies

Areca Catechu

199+

studies

Sp600125

117+

studies

Alsterpaullone

12+

studies

Ha1077

11+

studies

Kenpaullone

studies

All 51 Compounds — Ranked by Evidence

Gefitinib

5.67

confidence

Foretinib

4.34

confidence

Bosutinib

4.08

confidence

Doramapimod

4.06

confidence

Bi 2536

4.01

confidence

Brigatinib

3.81

confidence

Neratinib

3.66

confidence

Tae 684

3.43

confidence

Mln 8054

3.33

confidence

Lestaurtinib

3.04

confidence

Pf 03758309

3.00

confidence

Hymenialdisine

3.00

confidence

Ruboxistaurin

2.94

confidence

Defosbarasertib

2.89

confidence

Kw 2449

2.64

confidence

Gsk 690693

2.64

confidence

Isogranulatimide

2.56

confidence

Ast 487

2.56

confidence

Debromohymenialdisine

2.56

confidence

Su 014813

2.20

confidence

Prexasertib

2.08

confidence

Sra 737

1.95

confidence

Ucn 01

1.79

confidence

Ha1077

11+

studies

1.10

confidence

Alsterpaullone

12+

studies

1.10

confidence

Kenpaullone

studies

1.10

confidence

Sp600125

117+

studies

1.10

confidence

Ephedra Sinica

1.00

confidence

Agastache Rugosa

1.00

confidence

Allium Sativum

500+

studies

1.00

confidence

Allium Tuberosum

1.00

confidence

Aloe Vera

1.00

confidence

Anemarrhena Asphodeloides

1.00

confidence

Arctium Lappa

1.00

confidence

Areca Catechu

199+

studies

1.00

confidence

Artemisia Argyi

1.00

confidence

Artemisia Capillaris

1.00

confidence

Atractylodes Macrocephala

1.00

confidence

Bletilla Striata

1.00

confidence

Bombyx Mori

1.00

confidence

Bupleurum Chinense

1.00

confidence

Carthamus Tinctorius

1.00

confidence

Centella Asiatica

499+

studies

1.00

confidence

Chaenomeles Speciosa

1.00

confidence

Citrus Reticulata

1.00

confidence

Crataegus Pinnatifida

1.00

confidence

Curcuma Longa

500+

studies

1.00

confidence

Cynomorium Songaricum

1.00

confidence

Dimocarpus Longan

1.00

confidence

Eriobotrya Japonica

1.00

confidence

Lovastatin

300+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CHEK2 (checkpoint kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CHEK2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.