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BiohacksAI/Targets/CHEK2
MOLECULAR TARGETUniProt: O96017

CHEK2

checkpoint kinase 2

138 compounds · BiohacksAI corpus v20260307-01

138
compounds
Compounds
138
Gene Symbol
CHEK2
NCBI Gene
11200

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About CHEK2

CHEK2 (checkpoint kinase 2) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 138 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View CHEK2 on UniProt →
Compounds Targeting CHEK2 (50)
1
Gefitinib
5.67
confidence
2
Foretinib
4.34
confidence
3
Bosutinib
4.08
confidence
4
Doramapimod
4.06
confidence
5
Bi 2536
4.01
confidence
6
Brigatinib
3.81
confidence
7
Neratinib
3.66
confidence
8
Tae 684
3.43
confidence
9
Mln 8054
3.33
confidence
10
Lestaurtinib
3.04
confidence
11
Pf 03758309
3.00
confidence
12
Hymenialdisine
3.00
confidence
13
Ruboxistaurin
2.94
confidence
14
Defosbarasertib
2.89
confidence
15
Kw 2449
2.64
confidence
16
Gsk 690693
2.64
confidence
17
Isogranulatimide
2.56
confidence
18
Ast 487
2.56
confidence
19
Debromohymenialdisine
2.56
confidence
20
Su 014813
2.20
confidence
21
Prexasertib
2.08
confidence
22
Sra 737
1.95
confidence
23
Ucn 01
1.79
confidence
24
Ha1077
11
studies
1.10
confidence
25
Alsterpaullone
12
studies
1.10
confidence
26
Kenpaullone
8
studies
1.10
confidence
27
Sp600125
117
studies
1.10
confidence
28
Ephedra Sinica
1.00
confidence
29
Agastache Rugosa
1.00
confidence
30
Allium Sativum
500
studies
1.00
confidence
31
Allium Tuberosum
1.00
confidence
32
Aloe Vera
1.00
confidence
33
Anemarrhena Asphodeloides
1.00
confidence
34
Arctium Lappa
1.00
confidence
35
Areca Catechu
199
studies
1.00
confidence
36
Artemisia Argyi
1.00
confidence
37
Artemisia Capillaris
1.00
confidence
38
Atractylodes Macrocephala
1.00
confidence
39
Bletilla Striata
1.00
confidence
40
Bombyx Mori
1.00
confidence
41
Bupleurum Chinense
1.00
confidence
42
Carthamus Tinctorius
1.00
confidence
43
Centella Asiatica
499
studies
1.00
confidence
44
Chaenomeles Speciosa
1.00
confidence
45
Citrus Reticulata
1.00
confidence
46
Crataegus Pinnatifida
1.00
confidence
47
Curcuma Longa
500
studies
1.00
confidence
48
Cynomorium Songaricum
1.00
confidence
49
Dimocarpus Longan
1.00
confidence
50
Eriobotrya Japonica
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.