Compounds That Target CYP1A2

cytochrome P450 family 1 subfamily A member 2 · 371 compounds in BiohacksAI corpus

CYP1A2 (cytochrome P450 family 1 subfamily A member 2) is a cytochrome P450 enzyme involved in the metabolism of drugs, hormones, and dietary compounds. CYP enzymes are critical determinants of pharmacokinetics and drug-herb interactions. The 371 compounds listed here have documented interactions with CYP1A2 based on BindingDB inhibition and binding assay data, making this resource valuable for assessing compound safety and interaction profiles.

View CYP1A2 target page →UniProt: P05177 ↗

Most Studied Compounds for CYP1A2

Phenacetin

300+

studies

Apigenin

300+

studies

Quercetin

300+

studies

Genistein

300+

studies

Kaempferol

300+

studies

Methoxypsoralen

300+

studies

Piribedil

300+

studies

Daidzein

300+

studies

Diuron

300+

studies

Emodin

300+

studies

All 50 Compounds — Ranked by Evidence

Artemisinin

6.18

confidence

Nifedipine

5.34

confidence

Sb 203580

4.92

confidence

Primaquine

4.91

confidence

Ly 294002

4.84

confidence

Alpha Naphthoflavone

4.67

confidence

Propafenone

4.53

confidence

Thioridazine

4.52

confidence

Methoxsalen

4.22

confidence

Rilpivirine

4.20

confidence

Prochlorperazine

3.33

confidence

Phenothiazine

3.14

confidence

Benzylimidazole

2.89

confidence

Benzodefchrysene

2.89

confidence

3 Methylcholanthrene

2.77

confidence

Alosetron

2.77

confidence

Nabumetone

2.71

confidence

Phenacetin

300+

studies

2.64

confidence

Apigenin

300+

studies

2.56

confidence

Quercetin

300+

studies

2.48

confidence

Sulconazole

2.48

confidence

Melatonin

297+

studies

2.40

confidence

Disulfiram

297+

studies

2.40

confidence

1 Naphthylisothiocyanate

2.30

confidence

Chrysinflavonoids

2.30

confidence

Flutamide

298+

studies

2.30

confidence

Tenidap

2.30

confidence

Genistein

300+

studies

2.20

confidence

Kaempferol

300+

studies

2.20

confidence

Clotrimazoleheterocyclic

2.20

confidence

Methoxypsoralen

300+

studies

2.20

confidence

Piribedil

300+

studies

2.20

confidence

Riluzole

298+

studies

2.20

confidence

Sulindac

297+

studies

2.20

confidence

Thiabendazole

299+

studies

2.20

confidence

Mosapride

2.20

confidence

Daidzein

300+

studies

2.08

confidence

Isoniazid

299+

studies

2.08

confidence

Leflunomide

297+

studies

2.08

confidence

Nocodazole

215+

studies

2.08

confidence

Luteolin

150+

studies

1.95

confidence

Clofibratedrugage

1.95

confidence

Diuron

300+

studies

1.95

confidence

Emodin

300+

studies

1.95

confidence

Ethoxyquin

180+

studies

1.95

confidence

Indole

300+

studies

1.95

confidence

Menadione

300+

studies

1.95

confidence

Miconazole

298+

studies

1.95

confidence

Niclosamideorganic

1.95

confidence

Perphenazine

297+

studies

1.95

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CYP1A2 (cytochrome P450 family 1 subfamily A member 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CYP1A2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.