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BiohacksAI/Targets/CYP2C19/Compounds

Compounds That Target CYP2C19

cytochrome P450 family 2 subfamily C member 19 · 471 compounds in BiohacksAI corpus

CYP2C19 (cytochrome P450 family 2 subfamily C member 19) is a cytochrome P450 enzyme involved in the metabolism of drugs, hormones, and dietary compounds. CYP enzymes are critical determinants of pharmacokinetics and drug-herb interactions. The 471 compounds listed here have documented interactions with CYP2C19 based on BindingDB inhibition and binding assay data, making this resource valuable for assessing compound safety and interaction profiles.

View CYP2C19 target page →UniProt: P33261 ↗
Most Studied Compounds for CYP2C19
1
Norgestrel
300+
studies
2
Apigenin
300+
studies
3
Quercetin
300+
studies
4
Ethinyl Estradiol
300+
studies
5
Methoxypsoralen
300+
studies
6
Rotenone
300+
studies
7
Androstenedione
300+
studies
8
Carbaryl
300+
studies
9
Corticosterone
300+
studies
10
Menadione
300+
studies
All 50 Compounds — Ranked by Evidence
1
Sb 203580
4.92
confidence
2
Sirolimus
4.82
confidence
3
Thioridazine
4.52
confidence
4
Tranylcypromine
4.48
confidence
5
Nimodipine
4.29
confidence
6
Lansoprazole
4.01
confidence
7
Bupropion
3.93
confidence
8
Ticlopidine
3.85
confidence
9
R Bicalutamide
3.53
confidence
10
Oxybutynin
3.22
confidence
11
Idebenone
3.22
confidence
12
Fluorescein
3.09
confidence
13
Tolnaftate
2.71
confidence
14
Clemastine
2.56
confidence
15
Disulfiram
297+
studies
2.48
confidence
16
Sulconazole
2.48
confidence
17
Oxiconazole
2.48
confidence
18
Lacidipine
2.40
confidence
19
Clotrimazoleheterocyclic
2.20
confidence
20
Isoniazid
299+
studies
2.20
confidence
21
Levonorgestrel
292+
studies
2.20
confidence
22
Norgestrel
300+
studies
2.20
confidence
23
Mosapride
2.20
confidence
24
Apigenin
300+
studies
2.08
confidence
25
Quercetin
300+
studies
2.08
confidence
26
Ethinyl Estradiol
300+
studies
2.08
confidence
27
Finasteride
296+
studies
2.08
confidence
28
Flutamide
298+
studies
2.08
confidence
29
Methoxypsoralen
300+
studies
2.08
confidence
30
Rotenone
300+
studies
2.08
confidence
31
Androstenedione
300+
studies
1.95
confidence
32
Carbaryl
300+
studies
1.95
confidence
33
Chlorhexidine
299+
studies
1.95
confidence
34
Cimetidineorganic
1.95
confidence
35
Corticosterone
300+
studies
1.95
confidence
36
Ethoxyquin
180+
studies
1.95
confidence
37
Fulvestrant
295+
studies
1.95
confidence
38
Loratadine
296+
studies
1.95
confidence
39
Menadione
300+
studies
1.95
confidence
40
Piribedil
300+
studies
1.95
confidence
41
Riboflavin
297+
studies
1.95
confidence
42
Thiabendazole
299+
studies
1.95
confidence
43
Tolazamide
169+
studies
1.95
confidence
44
Tropicamide
1.95
confidence
45
Genistein
300+
studies
1.79
confidence
46
Progesterone
299+
studies
1.79
confidence
47
Colchicineheterocyclic
1.79
confidence
48
Fenofibrate
297+
studies
1.79
confidence
49
Lovastatin
300+
studies
1.79
confidence
50
Mestranol
300+
studies
1.79
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CYP2C19 (cytochrome P450 family 2 subfamily C member 19). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CYP2C19 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.