BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/CYP2C8/Compounds

Compounds That Target CYP2C8

cytochrome P450 family 2 subfamily C member 8 · 125 compounds in BiohacksAI corpus

CYP2C8 (cytochrome P450 family 2 subfamily C member 8) is a cytochrome P450 enzyme involved in the metabolism of drugs, hormones, and dietary compounds. CYP enzymes are critical determinants of pharmacokinetics and drug-herb interactions. The 125 compounds listed here have documented interactions with CYP2C8 based on BindingDB inhibition and binding assay data, making this resource valuable for assessing compound safety and interaction profiles.

View CYP2C8 target page →UniProt: P10632 ↗
Most Studied Compounds for CYP2C8
1
Simvastatin
1.0k+
studies
2
Raphanus Sativus
500+
studies
3
Portulaca Oleracea
500+
studies
4
Allium Sativum
500+
studies
5
Curcuma Longa
500+
studies
6
Centella Asiatica
499+
studies
7
Foeniculum Vulgare
499+
studies
8
Quercetin
300+
studies
9
Panax Ginseng
300+
studies
10
Imatinib Mesylate
300+
studies
All 56 Compounds — Ranked by Evidence
1
Liarozole
2.71
confidence
2
Quercetin
300+
studies
1.79
confidence
3
Phenelzine
297+
studies
1.10
confidence
4
Raphanus Sativus
500+
studies
1.00
confidence
5
Polygala Tenuifolia
1.00
confidence
6
Polygonum Cuspidatum
1.00
confidence
7
Portulaca Oleracea
500+
studies
1.00
confidence
8
Prunus Armeniaca
1.00
confidence
9
Prunus Mume
1.00
confidence
10
Quisqualis Indica
1.00
confidence
11
Agastache Rugosa
1.00
confidence
12
Allium Sativum
500+
studies
1.00
confidence
13
Allium Tuberosum
1.00
confidence
14
Aloe Vera
1.00
confidence
15
Arctium Lappa
1.00
confidence
16
Artemisia Argyi
1.00
confidence
17
Artemisia Capillaris
1.00
confidence
18
Aster Tataricus
1.00
confidence
19
Atractylodes Macrocephala
1.00
confidence
20
Bombyx Mori
1.00
confidence
21
Centella Asiatica
499+
studies
1.00
confidence
22
Chaenomeles Speciosa
1.00
confidence
23
Citrus Reticulata
1.00
confidence
24
Commiphora Myrrha
1.00
confidence
25
Curcuma Longa
500+
studies
1.00
confidence
26
Cynomorium Songaricum
1.00
confidence
27
Ephedra Sinica
1.00
confidence
28
Eriobotrya Japonica
1.00
confidence
29
Eucommia Ulmoides
1.00
confidence
30
Foeniculum Vulgare
499+
studies
1.00
confidence
31
Forsythia Suspensa
1.00
confidence
32
Fritillaria Cirrhosa
1.00
confidence
33
Gastrodia Elata
1.00
confidence
34
Gentiana Macrophylla
1.00
confidence
35
Ginkgo Biloba
299+
studies
1.00
confidence
36
Glycine Max
1.00
confidence
37
Glycyrrhiza Uralensis
1.00
confidence
38
Lilium Lancifolium
1.00
confidence
39
Litchi Chinensis
1.00
confidence
40
Lithospermum Erythrorhizon
1.00
confidence
41
Lobelia Chinensis
1.00
confidence
42
Lonicera Japonica
1.00
confidence
43
Morus Alba
1.00
confidence
44
Nelumbo Nucifera
1.00
confidence
45
Paeonia Lactiflora
1.00
confidence
46
Panax Ginseng
300+
studies
1.00
confidence
47
Panax Notoginseng
1.00
confidence
48
Perilla Frutescens
1.00
confidence
49
Pinellia Ternata
1.00
confidence
50
Piper Nigrum
1.00
confidence
51
Imatinib Mesylate
300+
studies
0.69
confidence
52
Loratadine
296+
studies
0.69
confidence
53
Gemfibrozil
297+
studies
0.69
confidence
54
Danazol
298+
studies
0.69
confidence
55
Clotrimazoleheterocyclic
0.69
confidence
56
Simvastatin
1.0k+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CYP2C8 (cytochrome P450 family 2 subfamily C member 8). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CYP2C8 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.