BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target ERBB2

erb-b2 receptor tyrosine kinase 2 · 74 compounds in BiohacksAI corpus

ERBB2 (erb-b2 receptor tyrosine kinase 2) is a biological target with 74 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into ERBB2 modulation for therapeutic and biohacking applications.

All 50 Compounds — Ranked by Evidence
1
Paclitaxel
7.17
confidence
2
Tamoxifen
5.88
confidence
3
Gefitinib
5.67
confidence
4
Erlotinib
5.55
confidence
5
Imatinib
5.47
confidence
6
Osimertinib
5.03
confidence
7
Sb 203580
4.92
confidence
8
Ibrutinib
4.86
confidence
9
Lapatinib
4.84
confidence
10
Alvocidib
4.52
confidence
11
Amiodarone
4.51
confidence
12
Foretinib
4.34
confidence
13
Vandetanib
4.30
confidence
14
Caffeic Acid Phenethyl Ester
4.25
confidence
15
Bosutinib
4.08
confidence
16
Fluphenazine
3.91
confidence
17
Brigatinib
3.81
confidence
18
Neratinib
3.66
confidence
19
Canertinib
3.53
confidence
20
Pelitinib
3.50
confidence
21
Candesartan
3.47
confidence
22
Tae 684
3.43
confidence
23
Acalabrutinib
3.22
confidence
24
Dacomitinib Anhydrous
3.14
confidence
25
Defosbarasertib
2.89
confidence
26
Bithionol
2.89
confidence
27
Pu H71
2.89
confidence
28
Benzodefchrysene
2.89
confidence
29
Cediranib
2.83
confidence
30
Masitinib
2.77
confidence
31
Closantel
2.71
confidence
32
Ebastine
2.64
confidence
33
Zanubrutinib
2.56
confidence
34
Cp 724714
2.56
confidence
35
Poziotinib
2.48
confidence
36
Tyrphostin 47
2.48
confidence
37
Cudc 101
2.40
confidence
38
Benzethonium Chloride
2.40
confidence
39
Tak 285
2.40
confidence
40
Aee 788
2.30
confidence
41
Cetylpyridinium Bromide
2.20
confidence
42
Iodoquinol
2.20
confidence
43
Mubritinib
2.20
confidence
44
Tg100 115
2.08
confidence
45
Enclomiphene
2.08
confidence
46
Canertinib Dihydrochloride
2.08
confidence
47
Lapatinib Ditosylate
2.08
confidence
48
Tyrphostin Ag 879
2.08
confidence
49
Maleimide
1.95
confidence
50
Bastadin 7
1.95
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ERBB2 (erb-b2 receptor tyrosine kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ERBB2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.