Compounds That Target ESR1
estrogen receptor 1 · 321 compounds in BiohacksAI corpus
ESR1 (estrogen receptor alpha) is a nuclear receptor that mediates estrogen signaling across reproductive, cardiovascular, and bone tissues. It is a major target for both therapeutic agents and dietary phytoestrogens such as genistein, daidzein, and lignans. The 321 compounds with documented ESR1 interactions span synthetic ligands, selective estrogen receptor modulators (SERMs), and naturally occurring plant compounds.
The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ESR1 (estrogen receptor 1). Confidence scores reflect the strength and breadth of experimental evidence.
Explore related resources: ESR1 target overview · All biological targets · Biological pathways
Data from BindingDB and PubMed. For research purposes only. Not medical advice.