Compounds That Target GRK2

G protein-coupled receptor kinase 2 · 125 compounds in BiohacksAI corpus

GRK2 (G protein-coupled receptor kinase 2) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 125 compounds with documented GRK2 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View GRK2 target page →UniProt: P25098 ↗

Most Studied Compounds for GRK2

Portulaca Oleracea

500+

studies

Raphanus Sativus

500+

studies

Curcuma Longa

500+

studies

Centella Asiatica

499+

studies

Panax Ginseng

300+

studies

Tetracycline

300+

studies

Cefixime

300+

studies

Hesperidin

300+

studies

Terbutaline

299+

studies

Streptonigrin

299+

studies

All 60 Compounds — Ranked by Evidence

Paroxetine

4.39

confidence

Pf 03758309

3.00

confidence

Sangivamycin

3.00

confidence

Capivasertib

2.77

confidence

Balanol

2.30

confidence

Ravoxertinib

2.08

confidence

Gsk 180736a

2.08

confidence

Scutellaria Baicalensis

1.00

confidence

Piper Nigrum

1.00

confidence

Polygala Tenuifolia

1.00

confidence

Polygonum Cuspidatum

1.00

confidence

Portulaca Oleracea

500+

studies

1.00

confidence

Prunus Armeniaca

1.00

confidence

Prunus Persica

1.00

confidence

Raphanus Sativus

500+

studies

1.00

confidence

Rehmannia Glutinosa

1.00

confidence

Salvia Miltiorrhiza

1.00

confidence

Scrophularia Ningpoensis

1.00

confidence

Agastache Rugosa

1.00

confidence

Allium Tuberosum

1.00

confidence

Aloe Vera

1.00

confidence

Apis Mellifera

1.00

confidence

Artemisia Capillaris

1.00

confidence

Aster Tataricus

1.00

confidence

Atractylodes Macrocephala

1.00

confidence

Bufo Bufo

1.00

confidence

Bupleurum Chinense

1.00

confidence

Carthamus Tinctorius

1.00

confidence

Centella Asiatica

499+

studies

1.00

confidence

Chaenomeles Speciosa

1.00

confidence

Citrus Reticulata

1.00

confidence

Curcuma Longa

500+

studies

1.00

confidence

Cuscuta Chinensis

1.00

confidence

Cynomorium Songaricum

1.00

confidence

Ephedra Sinica

1.00

confidence

Eriobotrya Japonica

1.00

confidence

Forsythia Suspensa

1.00

confidence

Gastrodia Elata

1.00

confidence

Glycine Max

1.00

confidence

Ligusticum Chuanxiong

1.00

confidence

Litchi Chinensis

1.00

confidence

Lithospermum Erythrorhizon

1.00

confidence

Lonicera Japonica

1.00

confidence

Morus Alba

1.00

confidence

Nelumbo Nucifera

1.00

confidence

Paeonia Lactiflora

1.00

confidence

Panax Ginseng

300+

studies

1.00

confidence

Panax Notoginseng

1.00

confidence

Perilla Frutescens

1.00

confidence

Pinellia Ternata

1.00

confidence

Tetracycline

300+

studies

0.69

confidence

Terbutaline

299+

studies

0.69

confidence

Streptonigrin

299+

studies

0.69

confidence

Isoproterenol

299+

studies

0.69

confidence

Flurandrenolone

65+

studies

0.69

confidence

Cefixime

300+

studies

0.69

confidence

Aurintricarboxylic Acid

184+

studies

0.69

confidence

Vitamin A

295+

studies

0.69

confidence

Hesperidin

300+

studies

0.69

confidence

Methylene Blue

200+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for GRK2 (G protein-coupled receptor kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: GRK2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.