Compounds That Target GRK4

G protein-coupled receptor kinase 4 · 48 compounds in BiohacksAI corpus

GRK4 (G protein-coupled receptor kinase 4) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 48 compounds with documented GRK4 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View GRK4 target page →UniProt: P32298 ↗

Most Studied Compounds for GRK4

Allium Sativum

500+

studies

Curcuma Longa

500+

studies

Portulaca Oleracea

500+

studies

Panax Ginseng

300+

studies

Axitinib

298+

studies

Crizotinib

298+

studies

All 48 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Tozasertib

4.33

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Nintedanib

3.61

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Dovitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Ruboxistaurin

2.94

confidence

R 406

2.83

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Gsk 461364

2.40

confidence

Balanol

2.30

confidence

Su 014813

2.20

confidence

Tg100 115

2.08

confidence

Axitinib

298+

studies

0.69

confidence

Crizotinib

298+

studies

0.69

confidence

Allium Sativum

500+

studies

0.50

confidence

Aloe Vera

0.50

confidence

Apis Mellifera

0.50

confidence

Bombyx Mori

0.50

confidence

Bupleurum Chinense

0.50

confidence

Carthamus Tinctorius

0.50

confidence

Cimicifuga Heracleifolia

0.50

confidence

Citrus Reticulata

0.50

confidence

Coix Lacryma

0.50

confidence

Corydalis Yanhusuo

0.50

confidence

Curcuma Longa

500+

studies

0.50

confidence

Cuscuta Chinensis

0.50

confidence

Forsythia Suspensa

0.50

confidence

Hirudo Nipponia

0.50

confidence

Lindera Aggregata

0.50

confidence

Lonicera Japonica

0.50

confidence

Panax Ginseng

300+

studies

0.50

confidence

Perilla Frutescens

0.50

confidence

Pinellia Ternata

0.50

confidence

Polygonum Cuspidatum

0.50

confidence

Portulaca Oleracea

500+

studies

0.50

confidence

Prunella Vulgaris

0.50

confidence

Prunus Armeniaca

0.50

confidence

Prunus Mume

0.50

confidence

Scolopendra Subspinipes

0.50

confidence

Scutellaria Baicalensis

0.50

confidence

Smilax Glabra

0.50

confidence

Ziziphus Jujuba

0.50

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for GRK4 (G protein-coupled receptor kinase 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: GRK4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.