Compounds That Target GSK3A

glycogen synthase kinase 3 alpha · 65 compounds in BiohacksAI corpus

GSK3A (glycogen synthase kinase 3 alpha) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 65 compounds targeting GSK3A include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

View GSK3A target page →UniProt: P49840 ↗

Most Studied Compounds for GSK3A

Indirubin

300+

studies

Apigenin

300+

studies

Kaempferol

300+

studies

Quercetin

300+

studies

Tannic Acid

300+

studies

Luteolin

150+

studies

Fisetin

78+

studies

Alsterpaullone

12+

studies

Kenpaullone

studies

All 50 Compounds — Ranked by Evidence

Alvocidib

4.52

confidence

Dinaciclib

3.87

confidence

Midostaurin

3.85

confidence

Silmitasertib

3.78

confidence

Abemaciclib

3.66

confidence

Nintedanib

3.61

confidence

Sb 216763

3.53

confidence

6bio

3.50

confidence

Bms 387032

3.47

confidence

Manzamine A

3.40

confidence

At 7519

3.33

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Pf 03758309

3.00

confidence

Ruboxistaurin

2.94

confidence

R 406

2.83

confidence

Pf 00562271

2.77

confidence

Sotrastaurin

2.77

confidence

Azd 5438

2.71

confidence

Laduviglusib

2.71

confidence

Gsk 690693

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Atuveciclib

2.56

confidence

Defactinib

2.48

confidence

Aloisine A

2.40

confidence

Berzosertib

2.30

confidence

Y 39983

2.20

confidence

Encorafenib

2.20

confidence

Bgt 226 Free Base

2.20

confidence

Leucettamine B

2.20

confidence

Enzastaurin

2.08

confidence

Rg 547

2.08

confidence

Ravoxertinib

2.08

confidence

Zemirciclib

2.08

confidence

Gsk 269962a

2.08

confidence

Ly 2090314

1.79

confidence

Alsterpaullone

12+

studies

1.61

confidence

Indirubin

300+

studies

1.39

confidence

Kenpaullone

studies

1.39

confidence

Myricetinflavonoids

1.10

confidence

Apigenin

300+

studies

0.69

confidence

Chrysinflavonoids

0.69

confidence

Fisetin

78+

studies

0.69

confidence

Kaempferol

300+

studies

0.69

confidence

Luteolin

150+

studies

0.69

confidence

Quercetin

300+

studies

0.69

confidence

Tannic Acid

300+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for GSK3A (glycogen synthase kinase 3 alpha). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: GSK3A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.