Compounds That Target HCK

HCK proto-oncogene, Src family tyrosine kinase · 56 compounds in BiohacksAI corpus

HCK (HCK proto-oncogene, Src family tyrosine kinase) is a biological target with 56 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HCK modulation for therapeutic and biohacking applications.

View HCK target page →UniProt: P08631 ↗

All 50 Compounds — Ranked by Evidence

Gefitinib

5.67

confidence

Erlotinib

5.55

confidence

Ibrutinib

4.86

confidence

Cabozantinib

4.39

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ponatinib

4.26

confidence

Nilotinib

4.17

confidence

Bosutinib

4.08

confidence

Doramapimod

4.06

confidence

Midostaurin

3.85

confidence

Brigatinib

3.81

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Mln 8054

3.33

confidence

Saracatinib

3.33

confidence

Dabrafenib

3.30

confidence

Neflamapimod

3.30

confidence

Alisertib

3.30

confidence

Dovitinib

3.09

confidence

At 9283

3.09

confidence

Dasatinib Anhydrous

3.09

confidence

Lestaurtinib

3.04

confidence

Ruboxistaurin

2.94

confidence

Danusertib

2.94

confidence

Defosbarasertib

2.89

confidence

Barasertib

2.89

confidence

R 406

2.83

confidence

Cediranib

2.83

confidence

Milciclib

2.77

confidence

Masitinib

2.77

confidence

Plx 4720

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Raf 265

2.48

confidence

Motesanib

2.48

confidence

Brivanib

2.48

confidence

Azd 7762

2.30

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Golvatinib

2.20

confidence

Cyc 116

2.08

confidence

Asp 3026

2.08

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HCK (HCK proto-oncogene, Src family tyrosine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HCK target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.