BiohacksAI/Targets/HCK

MOLECULAR TARGETUniProt: P08631

HCK

HCK proto-oncogene, Src family tyrosine kinase

56 compounds · BiohacksAI corpus v20260307-01

compounds

Compounds

Gene Symbol

HCK

NCBI Gene

3055

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About HCK

HCK (HCK proto-oncogene, Src family tyrosine kinase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 56 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View HCK on UniProt →

Compounds Targeting HCK (50)

Gefitinib

5.67

confidence

Erlotinib

5.55

confidence

Ibrutinib

4.86

confidence

Cabozantinib

4.39

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ponatinib

4.26

confidence

Nilotinib

4.17

confidence

Bosutinib

4.08

confidence

Doramapimod

4.06

confidence

Midostaurin

3.85

confidence

Brigatinib

3.81

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Mln 8054

3.33

confidence

Saracatinib

3.33

confidence

Dabrafenib

3.30

confidence

Neflamapimod

3.30

confidence

Alisertib

3.30

confidence

Dovitinib

3.09

confidence

At 9283

3.09

confidence

Dasatinib Anhydrous

3.09

confidence

Lestaurtinib

3.04

confidence

Ruboxistaurin

2.94

confidence

Danusertib

2.94

confidence

Defosbarasertib

2.89

confidence

Barasertib

2.89

confidence

R 406

2.83

confidence

Cediranib

2.83

confidence

Milciclib

2.77

confidence

Masitinib

2.77

confidence

Plx 4720

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Raf 265

2.48

confidence

Motesanib

2.48

confidence

Brivanib

2.48

confidence

Azd 7762

2.30

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Golvatinib

2.20

confidence

Cyc 116

2.08

confidence

Asp 3026

2.08

confidence

Top 50 compounds by confidence score. Derived from BindingDB assay data.

Data Source

Corpusv20260307-01

SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.