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BiohacksAI/Targets/HIF1A/Compounds

Compounds That Target HIF1A

hypoxia inducible factor 1 subunit alpha · 96 compounds in BiohacksAI corpus

HIF1A (hypoxia inducible factor 1 subunit alpha) is a biological target with 96 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HIF1A modulation for therapeutic and biohacking applications.

View HIF1A target page →UniProt: Q16665 ↗
Most Studied Compounds for HIF1A
1
Cycloheximide
300+
studies
2
Topotecan
300+
studies
3
Strophanthidin
300+
studies
4
Gliotoxin
300+
studies
5
Harmaline
300+
studies
6
Bortezomib
300+
studies
7
Harmine
300+
studies
8
Digitoxigenin
300+
studies
9
Digoxigenin
300+
studies
10
Fusaric Acid
300+
studies
All 50 Compounds — Ranked by Evidence
1
Chaetocin
2.94
confidence
2
Dipyridyl
2.89
confidence
3
Emetine
298+
studies
2.20
confidence
4
Cycloheximide
300+
studies
2.08
confidence
5
Topotecan
300+
studies
1.79
confidence
6
Strophanthidin
300+
studies
1.39
confidence
7
Fccp
76+
studies
1.39
confidence
8
Gliotoxin
300+
studies
1.39
confidence
9
Oxatomide
128+
studies
1.10
confidence
10
Harmaline
300+
studies
1.10
confidence
11
Bortezomib
300+
studies
1.10
confidence
12
Tanespimycin
33+
studies
1.10
confidence
13
Loratadine
296+
studies
1.10
confidence
14
Harmine
300+
studies
1.10
confidence
15
Prunella Vulgaris
1.00
confidence
16
Quisqualis Indica
1.00
confidence
17
Morus Alba
1.00
confidence
18
Digitoxigenin
300+
studies
0.69
confidence
19
Digoxigenin
300+
studies
0.69
confidence
20
Digoxin
299+
studies
0.69
confidence
21
Epinephrine
299+
studies
0.69
confidence
22
Ethoxyquin
180+
studies
0.69
confidence
23
Fusaric Acid
300+
studies
0.69
confidence
24
Gedunin
54+
studies
0.69
confidence
25
Hesperetin
300+
studies
0.69
confidence
26
Sp600125
117+
studies
0.69
confidence
27
Tubercidin
300+
studies
0.69
confidence
28
Tyrphostin 9
2+
studies
0.69
confidence
29
Hydrocortisone
298+
studies
0.69
confidence
30
Mometasone Furoate
292+
studies
0.69
confidence
31
Niclosamideorganic
0.69
confidence
32
Nisoldipinedrugage
0.69
confidence
33
Oxytetracycline
300+
studies
0.69
confidence
34
Phenoxybenzamine Hydrochloride
21+
studies
0.69
confidence
35
Apigenin
300+
studies
0.69
confidence
36
Chrysinflavonoids
0.69
confidence
37
Cortisol
299+
studies
0.69
confidence
38
Egcg
300+
studies
0.69
confidence
39
Kaempferol
300+
studies
0.69
confidence
40
Quercetin
300+
studies
0.69
confidence
41
Resveratrol
298+
studies
0.69
confidence
42
2 Chloroadenosine
300+
studies
0.69
confidence
43
Ag490
14+
studies
0.69
confidence
44
Beclomethasone
300+
studies
0.69
confidence
45
Camptothecin
300+
studies
0.69
confidence
46
Celastrol
300+
studies
0.69
confidence
47
Clotrimazoleheterocyclic
0.69
confidence
48
Cycloserine
298+
studies
0.69
confidence
49
Dequalinium
136+
studies
0.69
confidence
50
Desoximetasone
86+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HIF1A (hypoxia inducible factor 1 subunit alpha). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HIF1A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.