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BiohacksAI/Targets/HMGCR/Compounds

Compounds That Target HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase · 128 compounds in BiohacksAI corpus

HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) is a biological target with 128 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HMGCR modulation for therapeutic and biohacking applications.

View HMGCR target page →UniProt: P04035 ↗
Most Studied Compounds for HMGCR
1
Simvastatin
1.0k+
studies
2
Atorvastatin
1.0k+
studies
3
Allium Sativum
500+
studies
4
Curcuma Longa
500+
studies
5
Centella Asiatica
499+
studies
6
Foeniculum Vulgare
499+
studies
7
Lovastatin
300+
studies
8
Ginkgo Biloba
299+
studies
9
Pravastatin
297+
studies
All 50 Compounds — Ranked by Evidence
1
Lovastatin
300+
studies
3.64
confidence
2
Rosuvastatin
3.56
confidence
3
Simvastatin
1.0k+
studies
2.94
confidence
4
Pravastatin
297+
studies
2.83
confidence
5
Atorvastatin
1.0k+
studies
2.64
confidence
6
Achyranthes Bidentata
1.00
confidence
7
Agastache Rugosa
1.00
confidence
8
Allium Sativum
500+
studies
1.00
confidence
9
Allium Tuberosum
1.00
confidence
10
Aloe Vera
1.00
confidence
11
Arctium Lappa
1.00
confidence
12
Artemisia Annua
1.00
confidence
13
Artemisia Argyi
1.00
confidence
14
Artemisia Capillaris
1.00
confidence
15
Aster Tataricus
1.00
confidence
16
Atractylodes Macrocephala
1.00
confidence
17
Bombyx Mori
1.00
confidence
18
Bupleurum Chinense
1.00
confidence
19
Carthamus Tinctorius
1.00
confidence
20
Centella Asiatica
499+
studies
1.00
confidence
21
Chaenomeles Speciosa
1.00
confidence
22
Citrus Reticulata
1.00
confidence
23
Cnidium Monnieri
1.00
confidence
24
Commiphora Myrrha
1.00
confidence
25
Crataegus Pinnatifida
1.00
confidence
26
Curcuma Longa
500+
studies
1.00
confidence
27
Cuscuta Chinensis
1.00
confidence
28
Cynomorium Songaricum
1.00
confidence
29
Ephedra Sinica
1.00
confidence
30
Epimedium Brevicornum
1.00
confidence
31
Eriobotrya Japonica
1.00
confidence
32
Eucommia Ulmoides
1.00
confidence
33
Foeniculum Vulgare
499+
studies
1.00
confidence
34
Forsythia Suspensa
1.00
confidence
35
Fritillaria Cirrhosa
1.00
confidence
36
Gastrodia Elata
1.00
confidence
37
Gentiana Macrophylla
1.00
confidence
38
Ginkgo Biloba
299+
studies
1.00
confidence
39
Glycine Max
1.00
confidence
40
Glycyrrhiza Uralensis
1.00
confidence
41
Inula Japonica
1.00
confidence
42
Ligusticum Chuanxiong
1.00
confidence
43
Lilium Lancifolium
1.00
confidence
44
Litchi Chinensis
1.00
confidence
45
Lithospermum Erythrorhizon
1.00
confidence
46
Lobelia Chinensis
1.00
confidence
47
Lonicera Japonica
1.00
confidence
48
Lycopus Lucidus
1.00
confidence
49
Magnolia Biondii
1.00
confidence
50
Mentha Haplocalyx
1.00
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HMGCR target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.