BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HMGCR
MOLECULAR TARGETUniProt: P04035

HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

128 compounds · BiohacksAI corpus v20260307-01

128
compounds
Compounds
128
Gene Symbol
HMGCR
NCBI Gene
3156

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About HMGCR

HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 128 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View HMGCR on UniProt →
Compounds Targeting HMGCR (50)
1
Lovastatin
300
studies
3.64
confidence
2
Rosuvastatin
3.56
confidence
3
Simvastatin
1000
studies
2.94
confidence
4
Pravastatin
297
studies
2.83
confidence
5
Atorvastatin
1000
studies
2.64
confidence
6
Achyranthes Bidentata
1.00
confidence
7
Agastache Rugosa
1.00
confidence
8
Allium Sativum
500
studies
1.00
confidence
9
Allium Tuberosum
1.00
confidence
10
Aloe Vera
1.00
confidence
11
Arctium Lappa
1.00
confidence
12
Artemisia Annua
1.00
confidence
13
Artemisia Argyi
1.00
confidence
14
Artemisia Capillaris
1.00
confidence
15
Aster Tataricus
1.00
confidence
16
Atractylodes Macrocephala
1.00
confidence
17
Bombyx Mori
1.00
confidence
18
Bupleurum Chinense
1.00
confidence
19
Carthamus Tinctorius
1.00
confidence
20
Centella Asiatica
499
studies
1.00
confidence
21
Chaenomeles Speciosa
1.00
confidence
22
Citrus Reticulata
1.00
confidence
23
Cnidium Monnieri
1.00
confidence
24
Commiphora Myrrha
1.00
confidence
25
Crataegus Pinnatifida
1.00
confidence
26
Curcuma Longa
500
studies
1.00
confidence
27
Cuscuta Chinensis
1.00
confidence
28
Cynomorium Songaricum
1.00
confidence
29
Ephedra Sinica
1.00
confidence
30
Epimedium Brevicornum
1.00
confidence
31
Eriobotrya Japonica
1.00
confidence
32
Eucommia Ulmoides
1.00
confidence
33
Foeniculum Vulgare
499
studies
1.00
confidence
34
Forsythia Suspensa
1.00
confidence
35
Fritillaria Cirrhosa
1.00
confidence
36
Gastrodia Elata
1.00
confidence
37
Gentiana Macrophylla
1.00
confidence
38
Ginkgo Biloba
299
studies
1.00
confidence
39
Glycine Max
1.00
confidence
40
Glycyrrhiza Uralensis
1.00
confidence
41
Inula Japonica
1.00
confidence
42
Ligusticum Chuanxiong
1.00
confidence
43
Lilium Lancifolium
1.00
confidence
44
Litchi Chinensis
1.00
confidence
45
Lithospermum Erythrorhizon
1.00
confidence
46
Lobelia Chinensis
1.00
confidence
47
Lonicera Japonica
1.00
confidence
48
Lycopus Lucidus
1.00
confidence
49
Magnolia Biondii
1.00
confidence
50
Mentha Haplocalyx
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.