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BiohacksAI/Targets/HSF1/Compounds

Compounds That Target HSF1

heat shock factor 1 · 125 compounds in BiohacksAI corpus

HSF1 (heat shock factor 1) is a biological target with 125 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HSF1 modulation for therapeutic and biohacking applications.

View HSF1 target page →UniProt: AAH94064 ↗
Most Studied Compounds for HSF1
1
Allium Sativum
500+
studies
2
Curcuma Longa
500+
studies
3
Centella Asiatica
499+
studies
4
Foeniculum Vulgare
499+
studies
5
Celastrol
300+
studies
6
Tubercidin
300+
studies
7
Geldanamycin
300+
studies
8
Panax Ginseng
300+
studies
9
Quercetin
300+
studies
10
Cycloheximide
300+
studies
All 60 Compounds — Ranked by Evidence
1
Dinaciclib
3.87
confidence
2
Anisomycin
247+
studies
1.79
confidence
3
Celastrol
300+
studies
1.61
confidence
4
Tubercidin
300+
studies
1.61
confidence
5
Geldanamycin
300+
studies
1.39
confidence
6
Lamivudine
299+
studies
1.10
confidence
7
Vigna Umbellata
1.00
confidence
8
Prunus Armeniaca
1.00
confidence
9
Prunus Mume
1.00
confidence
10
Rehmannia Glutinosa
1.00
confidence
11
Rubia Cordifolia
200+
studies
1.00
confidence
12
Salvia Miltiorrhiza
1.00
confidence
13
Sargassum Fusiforme
1.00
confidence
14
Schisandra Chinensis
1.00
confidence
15
Scutellaria Baicalensis
1.00
confidence
16
Smilax China
142+
studies
1.00
confidence
17
Smilax Glabra
1.00
confidence
18
Taraxacum Mongolicum
1.00
confidence
19
Vigna Radiata
1.00
confidence
20
Agastache Rugosa
1.00
confidence
21
Allium Sativum
500+
studies
1.00
confidence
22
Aloe Vera
1.00
confidence
23
Anemarrhena Asphodeloides
1.00
confidence
24
Arctium Lappa
1.00
confidence
25
Artemisia Argyi
1.00
confidence
26
Artemisia Capillaris
1.00
confidence
27
Centella Asiatica
499+
studies
1.00
confidence
28
Chaenomeles Speciosa
1.00
confidence
29
Cimicifuga Heracleifolia
1.00
confidence
30
Citrus Reticulata
1.00
confidence
31
Curcuma Longa
500+
studies
1.00
confidence
32
Cynomorium Songaricum
1.00
confidence
33
Ephedra Sinica
1.00
confidence
34
Eucommia Ulmoides
1.00
confidence
35
Foeniculum Vulgare
499+
studies
1.00
confidence
36
Forsythia Suspensa
1.00
confidence
37
Fritillaria Cirrhosa
1.00
confidence
38
Ginkgo Biloba
299+
studies
1.00
confidence
39
Lilium Lancifolium
1.00
confidence
40
Litchi Chinensis
1.00
confidence
41
Lobelia Chinensis
1.00
confidence
42
Lonicera Japonica
1.00
confidence
43
Morus Alba
1.00
confidence
44
Nelumbo Nucifera
1.00
confidence
45
Panax Ginseng
300+
studies
1.00
confidence
46
Panax Notoginseng
1.00
confidence
47
Perilla Frutescens
1.00
confidence
48
Pinellia Ternata
1.00
confidence
49
Piper Nigrum
1.00
confidence
50
Polygonum Cuspidatum
1.00
confidence
51
Quercetin
300+
studies
0.69
confidence
52
Cycloheximide
300+
studies
0.69
confidence
53
Gamma Aminobutyric Acid
300+
studies
0.69
confidence
54
Homoharringtonine
300+
studies
0.69
confidence
55
Nordihydroguaiaretic Acid
300+
studies
0.69
confidence
56
Phentolamine
300+
studies
0.69
confidence
57
Podofilox
14+
studies
0.69
confidence
58
Procaine Hcl
8+
studies
0.69
confidence
59
Torsemide
245+
studies
0.69
confidence
60
Triptolide
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HSF1 (heat shock factor 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HSF1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.