BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target IRAK4

interleukin 1 receptor associated kinase 4 · 35 compounds in BiohacksAI corpus

IRAK4 (interleukin 1 receptor associated kinase 4) is a biological target with 35 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into IRAK4 modulation for therapeutic and biohacking applications.

Most Studied Compounds for IRAK4
299+
studies
117+
studies
All 35 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Alvocidib
4.52
confidence
3
Tozasertib
4.33
confidence
4
Vandetanib
4.30
confidence
5
Ponatinib
4.26
confidence
6
Bosutinib
4.08
confidence
7
Bi 2536
4.01
confidence
8
Quizartinib
3.99
confidence
9
Nintedanib
3.61
confidence
10
Canertinib
3.53
confidence
11
Tae 684
3.43
confidence
12
Fedratinib
3.40
confidence
13
Gilteritinib
3.40
confidence
14
Dovitinib
3.09
confidence
15
Lestaurtinib
3.04
confidence
16
R 406
2.83
confidence
17
K 252a
2.83
confidence
18
Milciclib
2.77
confidence
19
Pf 00562271
2.77
confidence
20
Pha 665752
2.71
confidence
21
Crenolanib
2.71
confidence
22
Kw 2449
2.64
confidence
23
Azd 7762
2.30
confidence
24
Su 014813
2.20
confidence
25
Rebastinib
2.20
confidence
26
Cyc 116
2.08
confidence
27
Mk 2461
2.08
confidence
28
Whi P131
1.95
confidence
29
Pf 03814735
1.79
confidence
30
Ucn 01
1.79
confidence
31
Zimlovisertib
1.79
confidence
299+
studies
0.69
confidence
117+
studies
0.69
confidence
2+
studies
0.69
confidence
2+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for IRAK4 (interleukin 1 receptor associated kinase 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: IRAK4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.