BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGET

IRAK4

interleukin 1 receptor associated kinase 4

35 compounds · BiohacksAI corpus v20260307-01

35
compounds
Compounds
35
Gene Symbol
IRAK4
NCBI Gene
51135

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About IRAK4

IRAK4 (interleukin 1 receptor associated kinase 4) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 35 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting IRAK4 (35)
1
Gefitinib
5.67
confidence
2
Alvocidib
4.52
confidence
3
Tozasertib
4.33
confidence
4
Vandetanib
4.30
confidence
5
Ponatinib
4.26
confidence
6
Bosutinib
4.08
confidence
7
Bi 2536
4.01
confidence
8
Quizartinib
3.99
confidence
9
Nintedanib
3.61
confidence
10
Canertinib
3.53
confidence
11
Tae 684
3.43
confidence
12
Fedratinib
3.40
confidence
13
Gilteritinib
3.40
confidence
14
Dovitinib
3.09
confidence
15
Lestaurtinib
3.04
confidence
16
R 406
2.83
confidence
17
K 252a
2.83
confidence
18
Milciclib
2.77
confidence
19
Pf 00562271
2.77
confidence
20
Pha 665752
2.71
confidence
21
Crenolanib
2.71
confidence
22
Kw 2449
2.64
confidence
23
Azd 7762
2.30
confidence
24
Su 014813
2.20
confidence
25
Rebastinib
2.20
confidence
26
Cyc 116
2.08
confidence
27
Mk 2461
2.08
confidence
28
Whi P131
1.95
confidence
29
Pf 03814735
1.79
confidence
30
Ucn 01
1.79
confidence
31
Zimlovisertib
1.79
confidence
299
studies
0.69
confidence
117
studies
0.69
confidence
2
studies
0.69
confidence
2
studies
0.69
confidence
Top 35 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.