Compounds That Target JAK1

Tyrosine-protein kinase JAK1 · 59 compounds in BiohacksAI corpus

JAK1 (Tyrosine-protein kinase JAK1) is a biological target with 59 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into JAK1 modulation for therapeutic and biohacking applications.

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Most Studied Compounds for JAK1

Bdb Pf 06651600 Us11111242 Example 5 Us9617258 Example 5

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Bdb Asp 015k Asp015k Peficitinib

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Bdb Chembl4238926

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Bdb Chembl4446102

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Bdb E Z 2 Cyano N N Dimethyl 3 5 1 1s 2r 2 Methylcyclohexyl 1 6 Dihydroimidazo 4 5 D

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Bdb Pf 02384554 Us10966980 Example 8 Us9035074 8

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All 50 Compounds — Ranked by Evidence

Tofacitinib

4.65

confidence

Tozasertib

4.33

confidence

Ponatinib

4.26

confidence

Ruxolitinib

4.23

confidence

Ceritinib

4.19

confidence

Pi 103

4.17

confidence

Midostaurin

3.85

confidence

Nintedanib

3.61

confidence

Baricitinib

3.56

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Entrectinib

3.18

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Upadacitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Filgotinib

3.04

confidence

Momelotinib

2.89

confidence

R 406

2.83

confidence

Sotrastaurin

2.77

confidence

Ritlecitinib

2.77

confidence

Pha 665752

2.71

confidence

Apitolisib

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Motesanib

2.48

confidence

Deucravacitinib

2.48

confidence

Azd 1480

2.30

confidence

Reversine

2.30

confidence

Vs 5584

2.30

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Decernotinib

2.20

confidence

Gandotinib

2.20

confidence

Cyc 116

2.08

confidence

Tg100 115

2.08

confidence

Cerdulatinib

1.95

confidence

Itacitinib

1.95

confidence

Delgocitinib

1.95

confidence

Pf 03814735

1.79

confidence

Abrocitinib

1.79

confidence

Bdb Pf 06651600 Us11111242 Example 5 Us9617258 Example 5

studies

0.69

confidence

Bdb Asp 015k Asp015k Peficitinib

studies

0.69

confidence

Bdb Chembl4238926

studies

0.69

confidence

Bdb Chembl4446102

studies

0.69

confidence

Bdb E Z 2 Cyano N N Dimethyl 3 5 1 1s 2r 2 Methylcyclohexyl 1 6 Dihydroimidazo 4 5 D

studies

0.69

confidence

Bdb Pf 02384554 Us10966980 Example 8 Us9035074 8

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for JAK1 (Tyrosine-protein kinase JAK1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: JAK1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.