BiohacksAI/Targets/JAK1

MOLECULAR TARGET

JAK1

Tyrosine-protein kinase JAK1

59 compounds · BiohacksAI corpus v20260307-01

compounds

Compounds

Gene Symbol

JAK1

NCBI Gene

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About JAK1

JAK1 (Tyrosine-protein kinase JAK1) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 59 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting JAK1 (50)

Tofacitinib

4.65

confidence

Tozasertib

4.33

confidence

Ponatinib

4.26

confidence

Ruxolitinib

4.23

confidence

Ceritinib

4.19

confidence

Pi 103

4.17

confidence

Midostaurin

3.85

confidence

Nintedanib

3.61

confidence

Baricitinib

3.56

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Entrectinib

3.18

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Upadacitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Filgotinib

3.04

confidence

Momelotinib

2.89

confidence

R 406

2.83

confidence

Sotrastaurin

2.77

confidence

Ritlecitinib

2.77

confidence

Pha 665752

2.71

confidence

Apitolisib

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Motesanib

2.48

confidence

Deucravacitinib

2.48

confidence

Azd 1480

2.30

confidence

Reversine

2.30

confidence

Vs 5584

2.30

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Decernotinib

2.20

confidence

Gandotinib

2.20

confidence

Cyc 116

2.08

confidence

Tg100 115

2.08

confidence

Cerdulatinib

1.95

confidence

Itacitinib

1.95

confidence

Delgocitinib

1.95

confidence

Pf 03814735

1.79

confidence

Abrocitinib

1.79

confidence

Bdb Pf 06651600 Us11111242 Example 5 Us9617258 Example 5

studies

0.69

confidence

Bdb Asp 015k Asp015k Peficitinib

studies

0.69

confidence

Bdb Chembl4238926

studies

0.69

confidence

Bdb Chembl4446102

studies

0.69

confidence

Bdb E Z 2 Cyano N N Dimethyl 3 5 1 1s 2r 2 Methylcyclohexyl 1 6 Dihydroimidazo 4 5 D

studies

0.69

confidence

Bdb Pf 02384554 Us10966980 Example 8 Us9035074 8

studies

0.69

confidence

Top 50 compounds by confidence score. Derived from BindingDB assay data.

Data Source

Corpusv20260307-01

SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.