Compounds That Target MAP2K1

mitogen-activated protein kinase kinase 1 · 153 compounds in BiohacksAI corpus

MAP2K1 (mitogen-activated protein kinase kinase 1) is a biological target with 153 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MAP2K1 modulation for therapeutic and biohacking applications.

View MAP2K1 target page →UniProt: Q02750 ↗

Most Studied Compounds for MAP2K1

Allium Sativum

500+

studies

Arctigenin

300+

studies

Sorafenib

300+

studies

Dasatinib

299+

studies

Vemurafenib

298+

studies

Axitinib

298+

studies

Trametinib

296+

studies

Pd98059

studies

All 54 Compounds — Ranked by Evidence

Tofacitinib

4.65

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Naphthoquinone

3.58

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Gilteritinib

3.40

confidence

Fedratinib

3.40

confidence

Trametinib

296+

studies

3.22

confidence

Mirdametinib

3.18

confidence

Jnj 7706621

3.09

confidence

Dovitinib

3.09

confidence

Selumetinib

3.09

confidence

Lestaurtinib

3.04

confidence

Hymenialdisine

3.00

confidence

Ci 1040

2.94

confidence

Orantinib

2.89

confidence

Defosbarasertib

2.89

confidence

K 252a

2.83

confidence

R 406

2.83

confidence

Oroidin

2.77

confidence

Plx 4720

2.71

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Cobimetinib

2.64

confidence

Linsitinib

2.64

confidence

Debromohymenialdisine

2.56

confidence

Tak 285

2.40

confidence

Azd 7762

2.30

confidence

Binimetinib

2.30

confidence

Avutometinib

2.30

confidence

Su 014813

2.20

confidence

Amg 900

2.08

confidence

Cep 32496

1.95

confidence

Tak 733

1.95

confidence

Gsk 1059615

1.95

confidence

Pd98059

studies

1.79

confidence

Dasatinib

299+

studies

1.10

confidence

Allium Sativum

500+

studies

1.00

confidence

Aloe Vera

1.00

confidence

Artemisia Argyi

1.00

confidence

Artemisia Capillaris

1.00

confidence

Agastache Rugosa

1.00

confidence

Allium Tuberosum

1.00

confidence

Vemurafenib

298+

studies

0.69

confidence

Axitinib

298+

studies

0.69

confidence

Arctigenin

300+

studies

0.69

confidence

Sorafenib

300+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MAP2K1 (mitogen-activated protein kinase kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MAP2K1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.